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Sexual Health & Fertility

Libido, function, fertility, and reproductive health.

Ranked by evidence strength across reported benefits.

Herb#1· strong

Ginger

Culinary rhizome with strong antiemetic and anti-inflammatory effects.

Herb#2· strong

Saffron

Culinary spice with antidepressant effects comparable to SSRIs in mild-moderate depression.

Vitamin#3· strong

Vitamin B6 (Pyridoxine)

Cofactor for >100 enzymes including neurotransmitter synthesis.

Vitamin#4· strong

Folate (Vitamin B9)

One-carbon donor essential for DNA synthesis and neural tube development.

Mineral#5· strong

Iron

Oxygen-carrying mineral central to hemoglobin and cellular respiration.

Herb#6· strong

Tribulus Terrestris

Traditionally used for libido; testosterone-boosting claims not supported by trials.

Herb#7· strong

Chasteberry (Vitex)

Dopaminergic herb reducing prolactin and improving PMS/luteal phase symptoms.

Compound#8· strong

Myo-Inositol

Insulin sensitizer used for PCOS and anxiety/OCD support.

Compound#9· strong

Lactobacillus Probiotics

Lactic acid bacteria supporting gut barrier, immunity, and women's urogenital health.

Herb#10· strong

Tribulus Terrestris

Saponin-rich herb that improves libido (not testosterone) in human trials.

Vitamin#11· strong

Methylfolate (L-5-MTHF)

Bioactive folate that bypasses the MTHFR enzyme — preferred in MTHFR variants and pregnancy.

Herb#12· strong

Mucuna Pruriens (Velvet Bean)

Natural L-DOPA source studied for Parkinson's, libido, and fertility.

Herb#13· strong

Tribulus terrestris (Libido)

Steroidal saponin herb claimed for libido and sexual function.

Mineral#14· strong

Ferrous Sulfate

Standard low-cost iron salt — effective but commonly causes GI side effects.

Fatty Acid#15· strong

DHA (Prenatal)

Critical fatty acid for fetal brain and retinal development.

Herb#16· moderate

Tongkat Ali

Malaysian root extract that frees bound testosterone via SHBG reduction.

Mineral#17· moderate

Zinc

Cofactor for ~300 enzymes — critical for testosterone, immune function, and DNA synthesis.

Herb#18· moderate

Maca

Andean root associated with libido improvement and energy without hormone changes.

Herb#19· moderate

Fenugreek

Spice/herb traditionally for libido & glycemic control; modest free-T effects.

Compound#20· moderate

Choline

Essential nutrient for cell membranes, methylation, and acetylcholine synthesis.

Amino Acid#21· moderate

L-Arginine

Conditionally essential amino acid and direct nitric oxide precursor.

Herb#22· moderate

Panax Ginseng

Adaptogenic ginseng studied for fatigue, cognition, and erectile function.

Herb#23· moderate

Mucuna Pruriens

Natural L-DOPA source studied for mood, libido, and Parkinson's.

Herb#24· moderate

Pomegranate

Polyphenol-rich fruit converted by gut microbes to urolithin A (mitochondrial benefit).

Compound#25· moderate

Soy Isoflavones

Phytoestrogens with mild SERM effects on bone, hot flashes, and lipids.

Herb#26· moderate

Tongkat Ali (Eurycoma longifolia)

Malaysian root with moderate human evidence for raising free testosterone and reducing SHBG.

Compound#27· moderate

Myo-Inositol

Insulin-sensitizing sugar alcohol — first-line non-Rx option for PCOS.

Compound#28· moderate

Yohimbine

Alpha-2 antagonist — improves erection and fat loss in fasted state but cardiovascular caution.

Amino Acid#29· moderate

L-Citrulline

Arginine precursor with superior bioavailability for NO and pump-driven performance.

Compound#30· moderate

Shilajit

Himalayan mineral exudate rich in fulvic acid, studied for testosterone and fatigue.

Herb#31· moderate

Yohimbine

Alpha-2 adrenergic antagonist used for fat loss and ED; significant cardiovascular risks.

Compound#32· moderate

DIM (Diindolylmethane)

Cruciferous-derived compound modulating estrogen metabolism toward 2-OH pathway.

Herb#33· moderate

Saw Palmetto

5α-reductase-inhibiting berry extract — used for BPH and androgenic hair loss.

Compound#34· moderate

DIM (Diindolylmethane)

Cruciferous-vegetable metabolite that shifts estrogen metabolism toward 2-OH (protective) pathways.

Herb#35· moderate

Chasteberry (Vitex)

Dopaminergic herb that lowers prolactin and supports luteal-phase progesterone.

Herb#36· moderate

Maca (Lepidium meyenii)

Andean root traditionally used for libido and fertility — non-hormonal mechanism.

Herb#37· moderate

Mucuna Pruriens (Fertility)

L-DOPA-containing legume — improves sperm parameters and dopaminergic tone.

Compound#38· moderate

CoQ10 (Fertility)

Mitochondrial antioxidant — improves sperm and oocyte quality.

Amino Acid#39· moderate

L-Citrulline (NO Production)

Arginine precursor — most efficient way to raise plasma arginine and NO.

Vitamin#40· moderate

P-5-P (Pyridoxal-5-Phosphate)

Active coenzyme form of B6 — preferred over pyridoxine HCl for sensitive populations.

Mineral#41· moderate

Calcium

Major bone mineral; also critical for muscle contraction and nerve signaling.

Mushroom#42· moderate

Cordyceps

Medicinal fungus studied for aerobic capacity and immune modulation.

Herb#43· moderate

Saw Palmetto

Lipidosterolic extract used for BPH urinary symptoms.

Herb#44· moderate

Pygeum

African plum bark used for BPH urinary symptoms.

Herb#45· moderate

Stinging Nettle Root

Herbal for BPH and SHBG modulation, often paired with saw palmetto.

Herb#46· moderate

Black Cohosh

Standardized extract for menopausal vasomotor symptoms.

Herb#47· moderate

Spearmint Tea

Used for hirsutism in PCOS via mild anti-androgen effect.

Herb#48· moderate

Cranberry

Berry with PACs that inhibit E. coli adhesion to urothelium for UTI prevention.

Compound#49· moderate

D-Mannose

Simple sugar that binds E. coli fimbriae, flushing them from the urinary tract.

Herb#50· moderate

Black Cohosh

Phytotherapy for menopausal vasomotor symptoms — non-estrogenic but symptom-active.

Compound#51· moderate

D-Chiro-Inositol

Complementary inositol used in 40:1 myo-inositol ratio for PCOS.

Herb#52· moderate

Panax Ginseng (Sexual Health)

Korean red ginseng with RCT-level evidence for erectile dysfunction.

Mineral#53· moderate

Zinc (Sperm Health)

Concentrated in semen — essential for sperm production and testosterone.

Mineral#54· moderate

Iron Bisglycinate

Chelated ferrous iron — best-tolerated form with high absorption and minimal GI distress.

Mineral#55· moderate

Selenomethionine

Organic selenium form — preferred for thyroid (Hashimoto's) and antioxidant support.

Herb#56· moderate

Tongkat Ali (Physta)

Water-extracted standardized tongkat ali for testosterone and stress.

Compound#57· moderate

Icariin (Horny Goat Weed)

Active flavonoid from Epimedium acting as PDE5 inhibitor.

Compound#58· moderate

Lycopene

Tomato carotenoid linked with prostate and cardiovascular protection.

Mineral#59· moderate

Boron (Extra)

Trace mineral that modulates steroid hormones and bone.

Herb#60· moderate

Tongkat Ali (Fertility)

Standardized eurycomanone extract for sperm quality.

Compound#61· moderate

Myo-Inositol

Insulin sensitizer for PCOS and metabolic health.

Herb#62· moderate

Mucuna Pruriens

Velvet bean providing natural L-DOPA.

Herb#63· moderate

Nettle Root

Urtica dioica for BPH.

Compound#64· moderate

Beta-Sitosterol

Plant sterol for BPH and cholesterol.

Herb#65· moderate

Black Maca

Lepidium meyenii black variant for energy.

Herb#66· moderate

Red Maca

Lepidium meyenii red variant for prostate.

Herb#67· moderate

Chaste Tree (Vitex)

Vitex agnus-castus for PMS.

Compound#68· moderate

Genistein

Soy isoflavone with bone benefits.

Compound#69· moderate

S-Equol

Daidzein metabolite for menopause.

Compound#70· moderate

Pomegranate Extract

Punica granatum ellagitannins.

Herb#71· moderate

Cranberry Extract

Vaccinium macrocarpon for UTI prevention.

Compound#72· moderate

Royal Jelly

Queen bee secretion with 10-HDA.

Herb#73· moderate

Tongkat Ali Eurycomanone-Standardized

LJ100 standardized to 22% eurypeptides.

Herb#74· moderate

Stinging Nettle Root

Urtica dioica root for free testosterone.

Mineral#75· moderate

Boron Citrate

Boron for hormone modulation.

Mineral#76· moderate

Zinc Monomethionine (ZMA)

Zinc + magnesium + B6 for recovery.

Fatty Acid#77· moderate

Evening Primrose Oil

GLA omega-6 for skin and PMS.

Fatty Acid#78· limited

Evening Primrose Oil

Omega-6 source rich in GLA, used for atopic dermatitis and cyclical breast pain.

Compound#79· limited

Pumpkin Seed Oil

Cold-pressed seed oil studied for hair density and prostate health.

Mineral#80· limited

Boron

Trace mineral with modest effects on free testosterone and bone mineralization.

Herb#81· limited

Shatavari

Ayurvedic adaptogen used for female hormone balance and lactation support.

Herb#82· limited

Cistanche Tubulosa

Desert plant tonic for libido and cognition.

Herb#83· limited

Fadogia Agrestis

Nigerian shrub — popularized for testosterone support; sparse human data.

Herb#84· limited

Horny Goat Weed

PDE5-inhibiting flavonoid (icariin) used for libido and erectile support.

Herb#85· limited

Dong Quai

TCM herb traditionally used for menstrual and menopausal symptoms.

Herb#86· limited

Red Clover

Isoflavone-rich legume traditionally used for menopausal symptoms.

Herb#87· limited

Uva-Ursi

Antibacterial herb for acute uncomplicated UTI; alkaline urine required.

Compound#88· limited

Marine Protein Complex (AminoMar)

Proprietary marine-derived complex (AminoMar) clinically studied for thinning hair in women.

Herb#89· limited

Horny Goat Weed (Epimedium)

Icariin-rich herb with PDE5-inhibitor-like activity for erectile function.

Mineral#90· limited

Zinc Picolinate

Zinc chelated to picolinic acid — one of the most bioavailable oral forms.

Herb#91· limited

Pine Pollen

Phyto-androgen pollen containing trace testosterone and DHEA.

Herb#92· limited

Muira Puama

Brazilian "potency wood" used historically for libido.

Herb#93· limited

Topical Saw Palmetto

Topical lotion form for androgenetic alopecia.

Herb#94· limited

Fadogia Agrestis

African shrub touted for testosterone (rodent data only).

Herb#95· anecdotal

Fadogia Agrestis

African shrub popularized for testosterone; limited human data and toxicology concerns.