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Tongkat Ali (Physta)

Water-extracted standardized tongkat ali for testosterone and stress.

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Overview

Water-extracted standardized tongkat ali for testosterone and stress.

Natural sources
  • Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
  • Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
  • Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
Common forms
  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Forms & variants of Tongkat Ali

Different chemical forms of Tongkat Ali behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Mechanism of action

Eurycomanone reduces SHBG-bound testosterone and lowers cortisol.

Pathways
  • · Eurycomanone reduces SHBG-bound testosterone
  • · lowers cortisol

Effects on the body

Increases
free testosterone in stressed adults

Organ system effects

Evidence-based benefits

Raises free testosterone in stressed adults

Moderate evidence

Potential side effects

Common
  • · Insomnia if taken late
Rare
    Serious

      Drug interactions

      Prescription medications (general)
      Always disclose Tongkat Ali (Physta) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
      minor

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid if you are
      • ·Pregnant or breastfeeding (insufficient safety data)
      • ·Children under 18 (unless directed by a clinician)
      Avoid with these conditions
      • ·Hormone-sensitive cancers (breast, prostate, ovarian, uterine)
      Avoid / monitor with these medications
      • ·Hormonal contraceptives, HRT, tamoxifen, aromatase inhibitors

      Supplement interactions

      Pairs well with
      • A high-quality multivitamin
        Covers micronutrient cofactors that support most supplement pathways.
      • Omega-3 (EPA/DHA)
        Foundational anti-inflammatory support that complements most regimens.
      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      200 mg Physta
      Best form
      Most evidence is based on the standardized extract capsule form.
      Timing
      Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
      With food?
      Morning

      Where to buy

      Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Scientific evidence8Show studies
      RCTJ Int Soc Sports Nutr · 2013

      Tongkat ali on stress and hormones

      Talbott SM, et al.

      4-week DB-RCT in 63 moderately stressed adults.

      Key findings

      Physta lowered cortisol 16% and raised testosterone 37% vs placebo.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tongkat Ali (Physta) — Raises free testosterone in stressed adults

      Live PubMed search

      Live results for "Tongkat Ali (Physta) Raises free testosterone in stressed adults" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tongkat Ali (Physta) and "Raises free testosterone in stressed adults". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tongkat Ali (Physta) — randomized controlled trial

      Live PubMed search

      Live results for "Tongkat Ali (Physta) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tongkat Ali (Physta) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tongkat Ali (Physta) — meta-analysis

      Live PubMed search

      Live results for "Tongkat Ali (Physta) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tongkat Ali (Physta) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tongkat Ali (Physta) — pharmacokinetics

      Live PubMed search

      Live results for "Tongkat Ali (Physta) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tongkat Ali (Physta) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tongkat Ali (Physta) — safety adverse events

      Live PubMed search

      Live results for "Tongkat Ali (Physta) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tongkat Ali (Physta) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tongkat Ali (Physta) — dose response

      Live PubMed search

      Live results for "Tongkat Ali (Physta) dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tongkat Ali (Physta) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Tongkat Ali (Physta) — clinical evidence

      Live Scholar search

      Cross-database citation index for Tongkat Ali (Physta) as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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