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evidence · mechanism · dose
Supplements/Herb

Tongkat Ali (Physta)

Water-extracted standardized tongkat ali for testosterone and stress.

Testosterone SupportLibido & Sexual Health

Overview

Water-extracted standardized tongkat ali for testosterone and stress.

Natural sources
    Common forms

      Forms & variants of Tongkat Ali

      Different chemical forms of Tongkat Ali behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Tongkat Ali

      Malaysian root extract that frees bound testosterone via SHBG reduction.

      Parent
      Tongkat Ali (Eurycoma longifolia)

      Malaysian root with moderate human evidence for raising free testosterone and reducing SHBG.

      Fertility protocol
      Tongkat Ali (Fertility)

      Standardized eurycomanone extract for sperm quality.

      Mechanism of action

      Eurycomanone reduces SHBG-bound testosterone and lowers cortisol.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Raises free testosterone in stressed adults

        Moderate evidence

        Potential side effects

        Common
        • · Insomnia if taken late
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Safety & non-supplemental interactions

            Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

            Avoid if you are
            • ·Pregnant or breastfeeding (insufficient safety data)
            • ·Children under 18 (unless directed by a clinician)
            Avoid with these conditions
            • ·Hormone-sensitive cancers (breast, prostate, ovarian, uterine)
            Avoid / monitor with these medications
            • ·Hormonal contraceptives, HRT, tamoxifen, aromatase inhibitors

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            200 mg Physta
            With food?
            Morning

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Herb
            Tongkat Ali …
            Amazon
            Wide selection · fast shipping
            Herb
            Tongkat Ali …
            iHerb
            Global delivery · curated brands
            Herb
            Tongkat Ali …
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTJ Int Soc Sports Nutr · 2013

            Tongkat ali on stress and hormones

            Talbott SM, et al.

            4-week DB-RCT in 63 moderately stressed adults.

            Key findings

            Physta lowered cortisol 16% and raised testosterone 37% vs placebo.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Physta) — Raises free testosterone in stressed adults

            Live PubMed search

            Live results for "Tongkat Ali (Physta) Raises free testosterone in stressed adults" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tongkat Ali (Physta) and "Raises free testosterone in stressed adults". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Physta) — randomized controlled trial

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            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Physta) — meta-analysis

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            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Physta) — pharmacokinetics

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            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Physta) — safety adverse events

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            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Physta) — dose response

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            Key findings

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            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Tongkat Ali (Physta) — clinical evidence

            Live Scholar search

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            Key findings

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            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.