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evidence · mechanism · dose
Supplements/Herb

Tongkat Ali (Fertility)

Standardized eurycomanone extract for sperm quality.

Male FertilityLibido & Sexual Health

Overview

Standardized eurycomanone extract for sperm quality.

Natural sources
    Common forms

      Forms & variants of Tongkat Ali

      Different chemical forms of Tongkat Ali behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Tongkat Ali

      Malaysian root extract that frees bound testosterone via SHBG reduction.

      Parent
      Tongkat Ali (Eurycoma longifolia)

      Malaysian root with moderate human evidence for raising free testosterone and reducing SHBG.

      Physta water extract
      Tongkat Ali (Physta)

      Water-extracted standardized tongkat ali for testosterone and stress.

      Mechanism of action

      Reduces SHBG-bound testosterone; modulates Leydig cell steroidogenesis.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves sperm parameters in subfertile men

        Moderate evidence

        Potential side effects

        Common
        • · Insomnia if late
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Safety & non-supplemental interactions

            Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

            Avoid if you are
            • ·Pregnant or breastfeeding (insufficient safety data)
            • ·Children under 18 (unless directed by a clinician)

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            200 mg standardized
            With food?
            Morning

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Herb
            Tongkat Ali …
            Amazon
            Wide selection · fast shipping
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            Tongkat Ali …
            iHerb
            Global delivery · curated brands
            Herb
            Tongkat Ali …
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            CohortAsian J Androl · 2010

            Tongkat ali on idiopathic infertility

            Tambi MI, Imran MK

            Open trial in 75 men.

            Key findings

            Improved sperm concentration, motility, and morphology.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Fertility) — Improves sperm parameters in subfertile men

            Live PubMed search

            Live results for "Tongkat Ali (Fertility) Improves sperm parameters in subfertile men" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tongkat Ali (Fertility) and "Improves sperm parameters in subfertile men". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Fertility) — randomized controlled trial

            Live PubMed search

            Live results for "Tongkat Ali (Fertility) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tongkat Ali (Fertility) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Fertility) — meta-analysis

            Live PubMed search

            Live results for "Tongkat Ali (Fertility) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tongkat Ali (Fertility) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Fertility) — pharmacokinetics

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            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Fertility) — safety adverse events

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            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tongkat Ali (Fertility) — dose response

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            Live results for "Tongkat Ali (Fertility) dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

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            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Tongkat Ali (Fertility) — clinical evidence

            Live Scholar search

            Cross-database citation index for Tongkat Ali (Fertility) as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.