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Male Fertility

Sperm count, motility, and DNA integrity.

Ranked by evidence strength across reported benefits.

Vitamin#1· strong

Folate (Vitamin B9)

One-carbon donor essential for DNA synthesis and neural tube development.

Herb#2· strong

Chasteberry (Vitex)

Dopaminergic herb reducing prolactin and improving PMS/luteal phase symptoms.

Compound#3· strong

Myo-Inositol

Insulin sensitizer used for PCOS and anxiety/OCD support.

Vitamin#4· strong

Methylfolate (L-5-MTHF)

Bioactive folate that bypasses the MTHFR enzyme — preferred in MTHFR variants and pregnancy.

Herb#5· strong

Mucuna Pruriens (Velvet Bean)

Natural L-DOPA source studied for Parkinson's, libido, and fertility.

Herb#6· moderate

Tongkat Ali

Malaysian root extract that frees bound testosterone via SHBG reduction.

Mineral#7· moderate

Zinc

Cofactor for ~300 enzymes — critical for testosterone, immune function, and DNA synthesis.

Herb#8· moderate

Maca

Andean root associated with libido improvement and energy without hormone changes.

Compound#9· moderate

Choline

Essential nutrient for cell membranes, methylation, and acetylcholine synthesis.

Herb#10· moderate

Tongkat Ali (Eurycoma longifolia)

Malaysian root with moderate human evidence for raising free testosterone and reducing SHBG.

Compound#11· moderate

Yohimbine

Alpha-2 antagonist — improves erection and fat loss in fasted state but cardiovascular caution.

Compound#12· moderate

Shilajit

Himalayan mineral exudate rich in fulvic acid, studied for testosterone and fatigue.

Compound#13· moderate

DIM (Diindolylmethane)

Cruciferous-derived compound modulating estrogen metabolism toward 2-OH pathway.

Herb#14· moderate

Saw Palmetto

5α-reductase-inhibiting berry extract — used for BPH and androgenic hair loss.

Compound#15· moderate

DIM (Diindolylmethane)

Cruciferous-vegetable metabolite that shifts estrogen metabolism toward 2-OH (protective) pathways.

Herb#16· moderate

Maca (Lepidium meyenii)

Andean root traditionally used for libido and fertility — non-hormonal mechanism.

Herb#17· moderate

Mucuna Pruriens (Fertility)

L-DOPA-containing legume — improves sperm parameters and dopaminergic tone.

Compound#18· moderate

CoQ10 (Fertility)

Mitochondrial antioxidant — improves sperm and oocyte quality.

Herb#19· moderate

Saw Palmetto

Lipidosterolic extract used for BPH urinary symptoms.

Herb#20· moderate

Pygeum

African plum bark used for BPH urinary symptoms.

Herb#21· moderate

Stinging Nettle Root

Herbal for BPH and SHBG modulation, often paired with saw palmetto.

Herb#22· moderate

Panax Ginseng (Sexual Health)

Korean red ginseng with RCT-level evidence for erectile dysfunction.

Mineral#23· moderate

Zinc (Sperm Health)

Concentrated in semen — essential for sperm production and testosterone.

Mineral#24· moderate

Iron Bisglycinate

Chelated ferrous iron — best-tolerated form with high absorption and minimal GI distress.

Mineral#25· moderate

Selenomethionine

Organic selenium form — preferred for thyroid (Hashimoto's) and antioxidant support.

Compound#26· moderate

Lycopene

Tomato carotenoid linked with prostate and cardiovascular protection.

Mineral#27· moderate

Boron (Extra)

Trace mineral that modulates steroid hormones and bone.

Herb#28· moderate

Tongkat Ali (Fertility)

Standardized eurycomanone extract for sperm quality.

Herb#29· moderate

Mucuna Pruriens

Velvet bean providing natural L-DOPA.

Herb#30· moderate

Nettle Root

Urtica dioica for BPH.

Compound#31· moderate

Beta-Sitosterol

Plant sterol for BPH and cholesterol.

Herb#32· moderate

Black Maca

Lepidium meyenii black variant for energy.

Herb#33· moderate

Red Maca

Lepidium meyenii red variant for prostate.

Compound#34· moderate

Pomegranate Extract

Punica granatum ellagitannins.

Herb#35· moderate

Tongkat Ali Eurycomanone-Standardized

LJ100 standardized to 22% eurypeptides.

Herb#36· moderate

Stinging Nettle Root

Urtica dioica root for free testosterone.

Mineral#37· moderate

Boron Citrate

Boron for hormone modulation.

Mineral#38· moderate

Zinc Monomethionine (ZMA)

Zinc + magnesium + B6 for recovery.

Compound#39· limited

Pumpkin Seed Oil

Cold-pressed seed oil studied for hair density and prostate health.

Mineral#40· limited

Boron

Trace mineral with modest effects on free testosterone and bone mineralization.

Herb#41· limited

Fadogia Agrestis

Nigerian shrub — popularized for testosterone support; sparse human data.

Herb#42· limited

Horny Goat Weed (Epimedium)

Icariin-rich herb with PDE5-inhibitor-like activity for erectile function.

Mineral#43· limited

Zinc Picolinate

Zinc chelated to picolinic acid — one of the most bioavailable oral forms.

Herb#44· limited

Pine Pollen

Phyto-androgen pollen containing trace testosterone and DHEA.

Herb#45· limited

Topical Saw Palmetto

Topical lotion form for androgenetic alopecia.

Herb#46· limited

Fadogia Agrestis

African shrub touted for testosterone (rodent data only).

Herb#47· anecdotal

Fadogia Agrestis

African shrub popularized for testosterone; limited human data and toxicology concerns.