SYS ONLINE
Supplements/Mineral

Boron

Trace mineral implicated in steroid hormone metabolism and bone integrity.

Overview

Trace mineral implicated in steroid hormone metabolism and bone integrity.

Natural sources
  • Raisins
  • Avocado
  • Nuts
  • Beans
Common forms
  • Boric acid
  • Calcium fructoborate

Forms & variants of Boron

Different chemical forms of Boron behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Mechanism of action

Modulates SHBG and may extend half-life of vitamin D and steroid hormones.

Pathways
  • · Steroid metabolism
  • · Vitamin D metabolism

Effects on the body

Increases
Free testosterone (small RCT)
Decreases
SHBG

Organ system effects

Bones

Reduces calcium/magnesium excretion.

Evidence-based benefits

Modestly raises free T at 10 mg/d over 1 week

Limited evidence

Reduces dysmenorrhea pain

Limited evidence

Potential side effects

Common
    Rare
      Serious
      • · Toxic at industrial doses

      Drug interactions

      No notable interactions reported.

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid with these conditions
      • ·Hormone-sensitive cancers (breast, prostate, ovarian, uterine)
      Avoid / monitor with these medications
      • ·Hormonal contraceptives, HRT, tamoxifen, aromatase inhibitors

      Supplement interactions

      Pairs well with

      None listed.

      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      3–10 mg
      Upper safe limit
      20 mg

      Where to buy

      Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Scientific evidence (9)

      Systematic reviewIntegr Med (Encinitas) · 2015

      Nothing boring about boron

      Pizzorno L

      Review of boron's effects on bone, hormones, and inflammation.

      Key findings

      6–10 mg/d increased free testosterone and reduced inflammatory markers in short trials.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Boron — Modestly raises free T at 10 mg/d over 1 week

      Live PubMed search

      Live results for "Boron Modestly raises free T at 10 mg/d over 1 week" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Boron and "Modestly raises free T at 10 mg/d over 1 week". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Boron — Reduces dysmenorrhea pain

      Live PubMed search

      Live results for "Boron Reduces dysmenorrhea pain" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Boron and "Reduces dysmenorrhea pain". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Boron — randomized controlled trial

      Live PubMed search

      Live results for "Boron randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Boron and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Boron — meta-analysis

      Live PubMed search

      Live results for "Boron meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Boron and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Boron — pharmacokinetics

      Live PubMed search

      Live results for "Boron pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Boron and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Boron — safety adverse events

      Live PubMed search

      Live results for "Boron safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Boron and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Boron — dose response

      Live PubMed search

      Live results for "Boron dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Boron and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Boron — clinical evidence

      Live Scholar search

      Cross-database citation index for Boron as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.