Overview
Trace mineral that modulates steroid hormones and bone.
- Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)
- Fortified foods such as cereals, breads, plant milks, and table salt
- Mineral supplements as chelates, citrates, glycinates, or inorganic salts
- Chelated form (glycinate, bisglycinate, citrate, malate)
- Inorganic salt (oxide, sulfate, chloride)
- Liquid ionic solution
- Topical or transdermal preparation
Forms & variants of Boron
Different chemical forms of Boron behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Increases free testosterone and 17β-estradiol by reducing SHBG.
- · Increases free testosterone
- · 17β-estradiol by reducing SHBG
Effects on the body
Organ system effects
Boron (Extra) contributes to bone mineralization, osteoblast activity, or calcium-phosphate homeostasis.
Boron (Extra) influences androgen signaling, prostate health, or male reproductive function.
Evidence-based benefits
Raises free testosterone after 1 week
Moderate evidencePotential side effects
- · Boron (Extra) is generally well-tolerated at evidence-based doses
- · Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
- · Headache or transient fatigue reported by a small fraction of users
- · Allergic or hypersensitivity reaction (rash, itching, swelling)
- · Sleep disturbance if taken late in the day
- · Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Hormone-sensitive cancers (breast, prostate, ovarian, uterine)
- ·Hormonal contraceptives, HRT, tamoxifen, aromatase inhibitors
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Scientific evidence8Show studiesHide studies
Boron and steroid hormones
Naghii MR, et al.
1-week trial in 8 men taking 10 mg boron.
Increased free testosterone and decreased estradiol.
PubMed: Boron (Extra) — Raises free testosterone after 1 week
Live PubMed search
Live results for "Boron (Extra) Raises free testosterone after 1 week" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Boron (Extra) and "Raises free testosterone after 1 week". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Boron (Extra) — randomized controlled trial
Live PubMed search
Live results for "Boron (Extra) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Boron (Extra) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Boron (Extra) — meta-analysis
Live PubMed search
Live results for "Boron (Extra) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Boron (Extra) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Boron (Extra) — pharmacokinetics
Live PubMed search
Live results for "Boron (Extra) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Boron (Extra) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Boron (Extra) — safety adverse events
Live PubMed search
Live results for "Boron (Extra) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Boron (Extra) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Boron (Extra) — dose response
Live PubMed search
Live results for "Boron (Extra) dose response" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Boron (Extra) and "dose response". Filter by RCT, meta-analysis, or year on the results page.
Google Scholar: Boron (Extra) — clinical evidence
Live Scholar search
Cross-database citation index for Boron (Extra) as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.