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Supplements/Mineral

Boron (Extra)

Trace mineral that modulates steroid hormones and bone.

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Overview

Trace mineral that modulates steroid hormones and bone.

Natural sources
  • Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)
  • Fortified foods such as cereals, breads, plant milks, and table salt
  • Mineral supplements as chelates, citrates, glycinates, or inorganic salts
Common forms
  • Chelated form (glycinate, bisglycinate, citrate, malate)
  • Inorganic salt (oxide, sulfate, chloride)
  • Liquid ionic solution
  • Topical or transdermal preparation

Forms & variants of Boron

Different chemical forms of Boron behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Mechanism of action

Increases free testosterone and 17β-estradiol by reducing SHBG.

Pathways
  • · Increases free testosterone
  • · 17β-estradiol by reducing SHBG

Effects on the body

Increases
free testosterone after 1 week

Organ system effects

Bones

Boron (Extra) contributes to bone mineralization, osteoblast activity, or calcium-phosphate homeostasis.

Reproductive

Boron (Extra) influences androgen signaling, prostate health, or male reproductive function.

Evidence-based benefits

Raises free testosterone after 1 week

Moderate evidence

Potential side effects

Common
  • · Boron (Extra) is generally well-tolerated at evidence-based doses
  • · Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
  • · Headache or transient fatigue reported by a small fraction of users
Rare
  • · Allergic or hypersensitivity reaction (rash, itching, swelling)
  • · Sleep disturbance if taken late in the day
Serious
  • · Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing

Drug interactions

Prescription medications (general)
Always disclose Boron (Extra) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
minor

Safety & non-supplemental interactions

Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

Avoid with these conditions
  • ·Hormone-sensitive cancers (breast, prostate, ovarian, uterine)
Avoid / monitor with these medications
  • ·Hormonal contraceptives, HRT, tamoxifen, aromatase inhibitors

Supplement interactions

Pairs well with
  • A high-quality multivitamin
    Covers micronutrient cofactors that support most supplement pathways.
  • Omega-3 (EPA/DHA)
    Foundational anti-inflammatory support that complements most regimens.
Avoid combining with

No specific avoidances listed.

Dosing & bioavailability

Typical dose
6–10 mg
Best form
Most evidence is based on the chelated form (glycinate, bisglycinate, citrate, malate) form.
Timing
Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
With food?
With food

Where to buy

Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

Scientific evidence8Show studies
CohortJ Trace Elem Med Biol · 2011

Boron and steroid hormones

Naghii MR, et al.

1-week trial in 8 men taking 10 mg boron.

Key findings

Increased free testosterone and decreased estradiol.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Boron (Extra) — Raises free testosterone after 1 week

Live PubMed search

Live results for "Boron (Extra) Raises free testosterone after 1 week" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Boron (Extra) and "Raises free testosterone after 1 week". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Boron (Extra) — randomized controlled trial

Live PubMed search

Live results for "Boron (Extra) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Boron (Extra) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Boron (Extra) — meta-analysis

Live PubMed search

Live results for "Boron (Extra) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Boron (Extra) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Boron (Extra) — pharmacokinetics

Live PubMed search

Live results for "Boron (Extra) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Boron (Extra) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Boron (Extra) — safety adverse events

Live PubMed search

Live results for "Boron (Extra) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Boron (Extra) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Boron (Extra) — dose response

Live PubMed search

Live results for "Boron (Extra) dose response" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Boron (Extra) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewGoogle Scholar · 1970

Google Scholar: Boron (Extra) — clinical evidence

Live Scholar search

Cross-database citation index for Boron (Extra) as it relates to "clinical evidence".

Key findings

Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

Open study
Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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