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evidence · mechanism · dose
Supplements/Compound

Pumpkin Seed Oil

aka Cucurbita pepo

Cold-pressed seed oil studied for hair density and prostate health.

Hair SupportMen's HealthGeneral Wellness

Overview

Cold-pressed seed oil studied for hair density and prostate health.

Natural sources
    Common forms

      Mechanism of action

      Phytosterols (β-sitosterol, delta-7 sterols) may inhibit 5α-reductase; rich in zinc and EFAs.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Increased hair count vs placebo in men with AGA (Cho 2014)

        Limited evidence

        Improved BPH-related QoL

        Limited evidence

        Potential side effects

        Common
          Rare
            Serious

              Drug interactions

              No notable interactions reported.

              Supplement interactions

              Pairs well with

              None listed.

              Avoid combining with

              No specific avoidances listed.

              Dosing & bioavailability

              Typical dose
              400 mg × 2/d (study dose)
              With food?
              With food

              Where to buy

              Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

              Compound
              Pumpkin Seed…
              Amazon
              Wide selection · fast shipping
              Compound
              Pumpkin Seed…
              iHerb
              Global delivery · curated brands
              Compound
              Pumpkin Seed…
              Thorne
              Practitioner-grade · NSF tested

              Scientific evidence (9)

              RCTEvid Based Complement Alternat Med · 2014

              Pumpkin seed oil and hair growth in androgenetic alopecia

              Cho YH, et al.

              24-week RCT of 400 mg/d pumpkin seed oil.

              Key findings

              40% increase in hair count vs placebo.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Pumpkin Seed Oil — Increased hair count vs placebo in men with AGA

              Live PubMed search

              Live results for "Pumpkin Seed Oil Increased hair count vs placebo in men with AGA" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Pumpkin Seed Oil and "Increased hair count vs placebo in men with AGA". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Pumpkin Seed Oil — Improved BPH-related QoL

              Live PubMed search

              Live results for "Pumpkin Seed Oil Improved BPH-related QoL" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Pumpkin Seed Oil and "Improved BPH-related QoL". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Pumpkin Seed Oil — randomized controlled trial

              Live PubMed search

              Live results for "Pumpkin Seed Oil randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Pumpkin Seed Oil and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Pumpkin Seed Oil — meta-analysis

              Live PubMed search

              Live results for "Pumpkin Seed Oil meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Pumpkin Seed Oil and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Pumpkin Seed Oil — pharmacokinetics

              Live PubMed search

              Live results for "Pumpkin Seed Oil pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Pumpkin Seed Oil and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Pumpkin Seed Oil — safety adverse events

              Live PubMed search

              Live results for "Pumpkin Seed Oil safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Pumpkin Seed Oil and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Pumpkin Seed Oil — dose response

              Live PubMed search

              Live results for "Pumpkin Seed Oil dose response" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Pumpkin Seed Oil and "dose response". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewGoogle Scholar · 1970

              Google Scholar: Pumpkin Seed Oil — clinical evidence

              Live Scholar search

              Cross-database citation index for Pumpkin Seed Oil as it relates to "clinical evidence".

              Key findings

              Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

              Open study
              Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.