Overview
Cold-pressed seed oil studied for hair density and prostate health.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Phytosterols (β-sitosterol, delta-7 sterols) may inhibit 5α-reductase; rich in zinc and EFAs.
- · Phytosterols (β-sitosterol, delta-7 sterols) may inhibit 5α-reductase
- · rich in zinc
Effects on the body
Organ system effects
Pumpkin Seed Oil influences androgen signaling, prostate health, or male reproductive function.
Evidence-based benefits
Increased hair count vs placebo in men with AGA (Cho 2014)
Limited evidenceImproved BPH-related QoL
Limited evidencePotential side effects
- · Pumpkin Seed Oil is generally well-tolerated at evidence-based doses
- · Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
- · Headache or transient fatigue reported by a small fraction of users
- · Allergic or hypersensitivity reaction (rash, itching, swelling)
- · Sleep disturbance if taken late in the day
- · Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence9Show studiesHide studies
Pumpkin seed oil and hair growth in androgenetic alopecia
Cho YH, et al.
24-week RCT of 400 mg/d pumpkin seed oil.
40% increase in hair count vs placebo.
PubMed: Pumpkin Seed Oil — Increased hair count vs placebo in men with AGA
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PubMed: Pumpkin Seed Oil — Improved BPH-related QoL
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PubMed: Pumpkin Seed Oil — randomized controlled trial
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PubMed: Pumpkin Seed Oil — meta-analysis
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PubMed: Pumpkin Seed Oil — pharmacokinetics
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PubMed: Pumpkin Seed Oil — safety adverse events
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PubMed: Pumpkin Seed Oil — dose response
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Google Scholar: Pumpkin Seed Oil — clinical evidence
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Cross-database citation index for Pumpkin Seed Oil as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.