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evidence · mechanism · dose
Supplements/Compound

Pomegranate Extract

Punica granatum ellagitannins.

Cardiovascular HealthMen's Health

Overview

Punica granatum ellagitannins.

Natural sources
    Common forms

      Mechanism of action

      Ellagitannins reduce LDL oxidation.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves carotid IMT

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            500–1000 mg

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Pomegranate …
            Amazon
            Wide selection · fast shipping
            Compound
            Pomegranate …
            iHerb
            Global delivery · curated brands
            Compound
            Pomegranate …
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTClin Nutr · 2004

            Pomegranate for atherosclerosis

            Aviram M, et al.

            19 patients

            Key findings

            Reduced carotid IMT 30%.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Pomegranate Extract — Improves carotid IMT

            Live PubMed search

            Live results for "Pomegranate Extract Improves carotid IMT" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Pomegranate Extract and "Improves carotid IMT". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Pomegranate Extract — randomized controlled trial

            Live PubMed search

            Live results for "Pomegranate Extract randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Pomegranate Extract and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Pomegranate Extract — meta-analysis

            Live PubMed search

            Live results for "Pomegranate Extract meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Pomegranate Extract and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Pomegranate Extract — pharmacokinetics

            Live PubMed search

            Live results for "Pomegranate Extract pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Pomegranate Extract and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Pomegranate Extract — safety adverse events

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            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Pomegranate Extract — dose response

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            Live results for "Pomegranate Extract dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Pomegranate Extract and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Pomegranate Extract — clinical evidence

            Live Scholar search

            Cross-database citation index for Pomegranate Extract as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.