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evidence · mechanism · dose
Supplements/Compound

CoQ10 (Fertility)

Mitochondrial antioxidant — improves sperm and oocyte quality.

Male FertilityFemale FertilitySperm HealthFertility

Overview

Mitochondrial antioxidant — improves sperm and oocyte quality.

Natural sources
    Common forms

      Mechanism of action

      Supports mitochondrial ATP in sperm midpiece and oocyte; reduces oxidative DNA damage.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves sperm count, motility, morphology

        Moderate evidence

        May improve oocyte quality in older women

        Limited evidence

        Potential side effects

        Common
          Rare
            Serious

              Drug interactions

              No notable interactions reported.

              Supplement interactions

              Pairs well with

              None listed.

              Avoid combining with

              No specific avoidances listed.

              Dosing & bioavailability

              Typical dose
              200–600 mg ubiquinol
              With food?
              With fat

              Where to buy

              Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

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              Thorne
              Practitioner-grade · NSF tested

              Scientific evidence (9)

              Meta-analysisJ Assist Reprod Genet · 2013

              CoQ10 and male/female fertility

              Lafuente R, et al.

              Meta-analysis of CoQ10 in male infertility.

              Key findings

              Improved sperm motility and concentration.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: CoQ10 (Fertility) — Improves sperm count, motility, morphology

              Live PubMed search

              Live results for "CoQ10 (Fertility) Improves sperm count, motility, morphology" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching CoQ10 (Fertility) and "Improves sperm count, motility, morphology". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: CoQ10 (Fertility) — May improve oocyte quality in older women

              Live PubMed search

              Live results for "CoQ10 (Fertility) May improve oocyte quality in older women" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching CoQ10 (Fertility) and "May improve oocyte quality in older women". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: CoQ10 (Fertility) — randomized controlled trial

              Live PubMed search

              Live results for "CoQ10 (Fertility) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching CoQ10 (Fertility) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: CoQ10 (Fertility) — meta-analysis

              Live PubMed search

              Live results for "CoQ10 (Fertility) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching CoQ10 (Fertility) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: CoQ10 (Fertility) — pharmacokinetics

              Live PubMed search

              Live results for "CoQ10 (Fertility) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching CoQ10 (Fertility) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: CoQ10 (Fertility) — safety adverse events

              Live PubMed search

              Live results for "CoQ10 (Fertility) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching CoQ10 (Fertility) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: CoQ10 (Fertility) — dose response

              Live PubMed search

              Live results for "CoQ10 (Fertility) dose response" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching CoQ10 (Fertility) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewGoogle Scholar · 1970

              Google Scholar: CoQ10 (Fertility) — clinical evidence

              Live Scholar search

              Cross-database citation index for CoQ10 (Fertility) as it relates to "clinical evidence".

              Key findings

              Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

              Open study
              Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.