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evidence · mechanism · dose
Supplements/Herb

Pygeum

aka Prunus africana

African plum bark used for BPH urinary symptoms.

Men's Health

Overview

African plum bark used for BPH urinary symptoms.

Natural sources
  • Prunus africana bark
Common forms
  • Standardized phytosterol extract

Mechanism of action

Phytosterols modulate prostatic inflammation and growth factors.

Pathways
  • · Anti-inflammatory prostatic

Effects on the body

Decreases
BPH symptoms

Organ system effects

Reproductive

Improves nocturia and IPSS.

Evidence-based benefits

Reduces BPH urinary symptoms

Moderate evidence

Potential side effects

Common
  • · GI upset
Rare
    Serious

      Drug interactions

      No notable interactions reported.

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid if you are
      • ·Pregnant or breastfeeding (insufficient safety data)
      • ·Children under 18 (unless directed by a clinician)

      Supplement interactions

      Pairs well with

      None listed.

      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      100–200 mg standardized

      Where to buy

      Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Herb
      Pygeum
      Amazon
      Wide selection · fast shipping
      Herb
      Pygeum
      iHerb
      Global delivery · curated brands
      Herb
      Pygeum
      Thorne
      Practitioner-grade · NSF tested

      Scientific evidence (8)

      Meta-analysisCochrane Database · 2002

      Pygeum africanum for benign prostatic hyperplasia

      Wilt T, et al.

      Cochrane review of 18 RCTs of Pygeum in BPH.

      Key findings

      Modest improvement in urologic symptoms.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Pygeum — Reduces BPH urinary symptoms

      Live PubMed search

      Live results for "Pygeum Reduces BPH urinary symptoms" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Pygeum and "Reduces BPH urinary symptoms". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Pygeum — randomized controlled trial

      Live PubMed search

      Live results for "Pygeum randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Pygeum and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Pygeum — meta-analysis

      Live PubMed search

      Live results for "Pygeum meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Pygeum and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Pygeum — pharmacokinetics

      Live PubMed search

      Live results for "Pygeum pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Pygeum and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Pygeum — safety adverse events

      Live PubMed search

      Live results for "Pygeum safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Pygeum and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Pygeum — dose response

      Live PubMed search

      Live results for "Pygeum dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Pygeum and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Pygeum — clinical evidence

      Live Scholar search

      Cross-database citation index for Pygeum as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.