Overview
Tomato carotenoid linked with prostate and cardiovascular protection.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Potent singlet oxygen quencher; modulates IGF-1 and androgen signaling.
- · Potent singlet oxygen quencher
- · modulates IGF-1
- · androgen signaling
Effects on the body
Organ system effects
Lycopene influences androgen signaling, prostate health, or male reproductive function.
Lycopene supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
Evidence-based benefits
Lowers prostate-specific antigen in BPH/HG-PIN
Moderate evidencePotential side effects
- · Skin discoloration at very high intake
Drug interactions
Supplement interactions
- Omega-3Anti-inflammatory cardiovascular synergy.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Lycopene — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Lycopene third party tested NSF
CapsulesPre-measured Lycopene capsules — easiest for travel and consistent daily dosing without scoops or scales.Lycopene capsules
PowderBulk unflavored Lycopene powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Lycopene powder unflavored
Best sellersMost-purchased Lycopene products on Amazon — a quick way to see what's reviewed widely before you commit.Lycopene best sellerScientific evidence8Show studiesHide studies
Lycopene in HG-PIN
Mohanty NK, et al.
1-year RCT in 40 men with HG-PIN.
4 mg bid lycopene reduced progression to prostate cancer vs control.
PubMed: Lycopene — Lowers prostate-specific antigen in BPH/HG-PIN
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PubMed: Lycopene — randomized controlled trial
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PubMed: Lycopene — meta-analysis
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PubMed: Lycopene — pharmacokinetics
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PubMed: Lycopene — dose response
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Google Scholar: Lycopene — clinical evidence
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