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evidence · mechanism · dose
Supplements/Compound

Beta-Sitosterol

Plant sterol for BPH and cholesterol.

Men's HealthCardiovascular Health

Overview

Plant sterol for BPH and cholesterol.

Natural sources
    Common forms

      Mechanism of action

      Inhibits cholesterol absorption; 5-AR effects.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces BPH symptoms

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            60–130 mg

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Beta-Sitoste…
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            iHerb
            Global delivery · curated brands
            Compound
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            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            Meta-analysisCochrane · 1999

            Beta-sitosterol in BPH

            Wilt T, et al.

            4 RCTs

            Key findings

            Improved urinary symptoms.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Beta-Sitosterol — Reduces BPH symptoms

            Live PubMed search

            Live results for "Beta-Sitosterol Reduces BPH symptoms" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Beta-Sitosterol and "Reduces BPH symptoms". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Beta-Sitosterol — randomized controlled trial

            Live PubMed search

            Live results for "Beta-Sitosterol randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Beta-Sitosterol and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Beta-Sitosterol — meta-analysis

            Live PubMed search

            Live results for "Beta-Sitosterol meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Beta-Sitosterol and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Beta-Sitosterol — pharmacokinetics

            Live PubMed search

            Live results for "Beta-Sitosterol pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Beta-Sitosterol and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Beta-Sitosterol — safety adverse events

            Live PubMed search

            Live results for "Beta-Sitosterol safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Beta-Sitosterol and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Beta-Sitosterol — dose response

            Live PubMed search

            Live results for "Beta-Sitosterol dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Beta-Sitosterol and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Beta-Sitosterol — clinical evidence

            Live Scholar search

            Cross-database citation index for Beta-Sitosterol as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.