Overview
African shrub touted for testosterone (rodent data only).
- Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
- Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
- Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Forms & variants of Fadogia Agrestis
Different chemical forms of Fadogia Agrestis behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Putative gonadotropin-mimetic in rats; mechanism in humans unclear.
- · Putative gonadotropin-mimetic in rats
- · mechanism in humans unclear
Effects on the body
Organ system effects
Fadogia Agrestis influences androgen signaling, prostate health, or male reproductive function.
Evidence-based benefits
Increases testosterone in rats
Limited evidencePotential side effects
- · Possible testicular toxicity at high doses
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
- ·Hormone-sensitive cancers (breast, prostate, ovarian, uterine)
- ·Hormonal contraceptives, HRT, tamoxifen, aromatase inhibitors
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified Fadogia Agrestis — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Fadogia Agrestis third party tested NSF
CapsulesPre-measured Fadogia Agrestis capsules — easiest for travel and consistent daily dosing without scoops or scales.Fadogia Agrestis capsules
PowderBulk unflavored Fadogia Agrestis powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Fadogia Agrestis powder unflavored
Best sellersMost-purchased Fadogia Agrestis products on Amazon — a quick way to see what's reviewed widely before you commit.Fadogia Agrestis best sellerScientific evidence8Show studiesHide studies
Fadogia in male rats
Yakubu MT, et al.
Rats given Fadogia extract for 5 days.
Increased serum testosterone; mild testicular changes at high dose.
PubMed: Fadogia Agrestis — Increases testosterone in rats
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PubMed: Fadogia Agrestis — randomized controlled trial
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PubMed: Fadogia Agrestis — meta-analysis
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PubMed: Fadogia Agrestis — pharmacokinetics
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PubMed: Fadogia Agrestis — dose response
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Google Scholar: Fadogia Agrestis — clinical evidence
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