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Tribulus terrestris (Libido)

Steroidal saponin herb claimed for libido and sexual function.

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Overview

Steroidal saponin herb claimed for libido and sexual function.

Natural sources
  • Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
  • Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
  • Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
Common forms
  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Forms & variants of Tribulus Terrestris

Different chemical forms of Tribulus Terrestris behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Mechanism of action

Protodioscin and steroidal saponins may modulate androgen receptors and NO.

Pathways
  • · Protodioscin
  • · steroidal saponins may modulate androgen receptors

Effects on the body

Supports
libido in postmenopausal women
Supports
No effect on testosterone in healthy men

Organ system effects

Reproductive

Tribulus terrestris (Libido) has documented effects on female reproductive endocrinology and cycle regulation.

Evidence-based benefits

Improves libido in postmenopausal women

Moderate evidence

No effect on testosterone in healthy men

Strong evidence

Potential side effects

Common
  • · GI upset
Rare
    Serious

      Drug interactions

      Prescription medications (general)
      Always disclose Tribulus terrestris (Libido) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
      minor

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid if you are
      • ·Pregnant or breastfeeding (insufficient safety data)
      • ·Children under 18 (unless directed by a clinician)

      Supplement interactions

      Pairs well with
      • A high-quality multivitamin
        Covers micronutrient cofactors that support most supplement pathways.
      • Omega-3 (EPA/DHA)
        Foundational anti-inflammatory support that complements most regimens.
      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      750 mg/day standardized
      Best form
      Most evidence is based on the standardized extract capsule form.
      Timing
      Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
      With food?
      With food

      Where to buy

      Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Scientific evidence9Show studies
      RCTGynecol Endocrinol · 2018

      Tribulus in women with HSDD

      Vale FBC, et al.

      120-day DB-RCT in 30 women with HSDD.

      Key findings

      Significant improvement in FSFI desire and lubrication scores.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tribulus terrestris (Libido) — Improves libido in postmenopausal women

      Live PubMed search

      Live results for "Tribulus terrestris (Libido) Improves libido in postmenopausal women" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "Improves libido in postmenopausal women". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tribulus terrestris (Libido) — No effect on testosterone in healthy men

      Live PubMed search

      Live results for "Tribulus terrestris (Libido) No effect on testosterone in healthy men" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "No effect on testosterone in healthy men". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tribulus terrestris (Libido) — randomized controlled trial

      Live PubMed search

      Live results for "Tribulus terrestris (Libido) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tribulus terrestris (Libido) — meta-analysis

      Live PubMed search

      Live results for "Tribulus terrestris (Libido) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tribulus terrestris (Libido) — pharmacokinetics

      Live PubMed search

      Live results for "Tribulus terrestris (Libido) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tribulus terrestris (Libido) — safety adverse events

      Live PubMed search

      Live results for "Tribulus terrestris (Libido) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Tribulus terrestris (Libido) — dose response

      Live PubMed search

      Live results for "Tribulus terrestris (Libido) dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Tribulus terrestris (Libido) — clinical evidence

      Live Scholar search

      Cross-database citation index for Tribulus terrestris (Libido) as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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