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evidence · mechanism · dose
Supplements/Herb

Tribulus terrestris (Libido)

Steroidal saponin herb claimed for libido and sexual function.

Libido & Sexual HealthWomen's Health

Overview

Steroidal saponin herb claimed for libido and sexual function.

Natural sources
    Common forms

      Forms & variants of Tribulus Terrestris

      Different chemical forms of Tribulus Terrestris behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Tribulus Terrestris

      Traditionally used for libido; testosterone-boosting claims not supported by trials.

      Parent
      Tribulus Terrestris

      Saponin-rich herb that improves libido (not testosterone) in human trials.

      Mechanism of action

      Protodioscin and steroidal saponins may modulate androgen receptors and NO.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves libido in postmenopausal women

        Moderate evidence

        No effect on testosterone in healthy men

        Strong evidence

        Potential side effects

        Common
        • · GI upset
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Safety & non-supplemental interactions

            Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

            Avoid if you are
            • ·Pregnant or breastfeeding (insufficient safety data)
            • ·Children under 18 (unless directed by a clinician)

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            750 mg/day standardized
            With food?
            With food

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Herb
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            Amazon
            Wide selection · fast shipping
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            iHerb
            Global delivery · curated brands
            Herb
            Tribulus ter…
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (9)

            RCTGynecol Endocrinol · 2018

            Tribulus in women with HSDD

            Vale FBC, et al.

            120-day DB-RCT in 30 women with HSDD.

            Key findings

            Significant improvement in FSFI desire and lubrication scores.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tribulus terrestris (Libido) — Improves libido in postmenopausal women

            Live PubMed search

            Live results for "Tribulus terrestris (Libido) Improves libido in postmenopausal women" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "Improves libido in postmenopausal women". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tribulus terrestris (Libido) — No effect on testosterone in healthy men

            Live PubMed search

            Live results for "Tribulus terrestris (Libido) No effect on testosterone in healthy men" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "No effect on testosterone in healthy men". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tribulus terrestris (Libido) — randomized controlled trial

            Live PubMed search

            Live results for "Tribulus terrestris (Libido) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tribulus terrestris (Libido) — meta-analysis

            Live PubMed search

            Live results for "Tribulus terrestris (Libido) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tribulus terrestris (Libido) — pharmacokinetics

            Live PubMed search

            Live results for "Tribulus terrestris (Libido) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tribulus terrestris (Libido) — safety adverse events

            Live PubMed search

            Live results for "Tribulus terrestris (Libido) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Tribulus terrestris (Libido) — dose response

            Live PubMed search

            Live results for "Tribulus terrestris (Libido) dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Tribulus terrestris (Libido) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Tribulus terrestris (Libido) — clinical evidence

            Live Scholar search

            Cross-database citation index for Tribulus terrestris (Libido) as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.