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evidence · mechanism · dose
Supplements/Herb

Ginger

aka Zingiber officinale

Culinary rhizome with strong antiemetic and anti-inflammatory effects.

Gut HealthChronic InflammationWomen's Health

Overview

Culinary rhizome with strong antiemetic and anti-inflammatory effects.

Natural sources
  • Zingiber officinale rhizome
Common forms
  • Fresh ginger
  • Standardized gingerols
  • Ginger oil

Mechanism of action

Gingerols/shogaols inhibit COX-2 and 5-HT3 receptors.

Pathways
  • · COX-2 inhibition
  • · 5-HT3 antagonism

Effects on the body

Decreases
Nausea
Decreases
Inflammation

Organ system effects

Digestive / Gut

Antiemetic in pregnancy and chemo.

Evidence-based benefits

Reduces nausea in pregnancy, motion sickness, and chemo

Strong evidence

Reduces osteoarthritis pain

Moderate evidence

Reduces dysmenorrhea pain

Moderate evidence

Potential side effects

Common
  • · Heartburn
Rare
    Serious

      Drug interactions

      Warfarin
      Mild antiplatelet effect.
      moderate

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid if you are
      • ·Pregnant or breastfeeding (insufficient safety data)
      • ·Children under 18 (unless directed by a clinician)
      • ·Late pregnancy — discuss with OB
      Avoid with these conditions
      • ·Gallstones (stimulates bile)
      • ·Bleeding disorders
      Avoid / monitor with these medications
      • ·Warfarin and anticoagulants
      • ·Antiplatelets, NSAIDs
      • ·Antidiabetic drugs
      • ·Antihypertensives
      Before surgery
      • ·Stop ≥2 weeks before surgery.

      Supplement interactions

      Pairs well with

      None listed.

      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      500–1000 mg standardized × 2–4/d

      Where to buy

      Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Herb
      Ginger
      Amazon
      Wide selection · fast shipping
      Herb
      Ginger
      iHerb
      Global delivery · curated brands
      Herb
      Ginger
      Thorne
      Practitioner-grade · NSF tested

      Scientific evidence (10)

      Meta-analysisNutr J · 2014

      Ginger for nausea and vomiting in pregnancy

      Viljoen E, et al.

      Meta-analysis of 12 RCTs of ginger in pregnancy nausea.

      Key findings

      Effective and well tolerated at 1 g/d.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Ginger — Reduces nausea in pregnancy, motion sickness, and chemo

      Live PubMed search

      Live results for "Ginger Reduces nausea in pregnancy, motion sickness, and chemo" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Ginger and "Reduces nausea in pregnancy, motion sickness, and chemo". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Ginger — Reduces osteoarthritis pain

      Live PubMed search

      Live results for "Ginger Reduces osteoarthritis pain" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Ginger and "Reduces osteoarthritis pain". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Ginger — Reduces dysmenorrhea pain

      Live PubMed search

      Live results for "Ginger Reduces dysmenorrhea pain" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Ginger and "Reduces dysmenorrhea pain". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Ginger — randomized controlled trial

      Live PubMed search

      Live results for "Ginger randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Ginger and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Ginger — meta-analysis

      Live PubMed search

      Live results for "Ginger meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Ginger and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Ginger — pharmacokinetics

      Live PubMed search

      Live results for "Ginger pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Ginger and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Ginger — safety adverse events

      Live PubMed search

      Live results for "Ginger safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Ginger and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Ginger — dose response

      Live PubMed search

      Live results for "Ginger dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Ginger and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Ginger — clinical evidence

      Live Scholar search

      Cross-database citation index for Ginger as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.