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evidence · mechanism · dose
Supplements/Herb

Fenugreek

aka Trigonella foenum-graecum · Testofen

Spice/herb traditionally for libido & glycemic control; modest free-T effects.

Testosterone SupportLibido & Sexual HealthBlood Sugar Management

Overview

Spice/herb traditionally for libido & glycemic control; modest free-T effects.

Natural sources
  • Trigonella seeds
Common forms
  • Testofen (Furosap)
  • Fenugreek seed powder

Mechanism of action

Furostanolic saponins may inhibit aromatase and 5-AR; soluble fiber lowers postprandial glucose.

Pathways
  • · 5-AR / aromatase modulation

Effects on the body

Supports
Free testosterone (small RCT)
Decreases
Postprandial glucose

Organ system effects

Reproductive

Improves libido and sexual function.

Evidence-based benefits

Improves libido and sexual function

Moderate evidence

Modestly raises free T

Limited evidence

Lowers postprandial glucose in T2D

Moderate evidence

Potential side effects

Common
  • · Maple-syrup body odor
  • · GI upset
Rare
    Serious

      Drug interactions

      Warfarin
      Coumarins.
      moderate
      Antidiabetics
      Hypoglycemia.
      moderate

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid if you are
      • ·Pregnant or breastfeeding (insufficient safety data)
      • ·Children under 18 (unless directed by a clinician)
      Avoid with these conditions
      • ·Hormone-sensitive cancers (breast, prostate, ovarian, uterine)
      Avoid / monitor with these medications
      • ·Hormonal contraceptives, HRT, tamoxifen, aromatase inhibitors

      Supplement interactions

      Pairs well with

      None listed.

      Avoid combining with
      • Pregnancy
        Uterine stimulant.

      Dosing & bioavailability

      Typical dose
      500–600 mg Testofen or 5 g whole seed

      Where to buy

      Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Herb
      Fenugreek
      Amazon
      Wide selection · fast shipping
      Herb
      Fenugreek
      iHerb
      Global delivery · curated brands
      Herb
      Fenugreek
      Thorne
      Practitioner-grade · NSF tested

      Scientific evidence (10)

      RCTJ Sport Health Sci · 2016

      Fenugreek extract on testosterone and exercise performance

      Wankhede S, et al.

      8-week RCT in resistance-trained males.

      Key findings

      Increased free testosterone and improved performance.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Fenugreek — Improves libido and sexual function

      Live PubMed search

      Live results for "Fenugreek Improves libido and sexual function" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Fenugreek and "Improves libido and sexual function". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Fenugreek — Modestly raises free T

      Live PubMed search

      Live results for "Fenugreek Modestly raises free T" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Fenugreek and "Modestly raises free T". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Fenugreek — Lowers postprandial glucose in T2D

      Live PubMed search

      Live results for "Fenugreek Lowers postprandial glucose in T2D" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Fenugreek and "Lowers postprandial glucose in T2D". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Fenugreek — randomized controlled trial

      Live PubMed search

      Live results for "Fenugreek randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Fenugreek and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Fenugreek — meta-analysis

      Live PubMed search

      Live results for "Fenugreek meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Fenugreek and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Fenugreek — pharmacokinetics

      Live PubMed search

      Live results for "Fenugreek pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Fenugreek and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Fenugreek — safety adverse events

      Live PubMed search

      Live results for "Fenugreek safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Fenugreek and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Fenugreek — dose response

      Live PubMed search

      Live results for "Fenugreek dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Fenugreek and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Fenugreek — clinical evidence

      Live Scholar search

      Cross-database citation index for Fenugreek as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.