Overview
Insulin sensitizer for PCOS and metabolic health.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Acts as insulin second messenger via inositol phosphoglycans.
- · Acts as insulin second messenger via inositol phosphoglycans
Effects on the body
Organ system effects
Myo-Inositol has documented effects on female reproductive endocrinology and cycle regulation.
Evidence-based benefits
Improves PCOS ovulation
Moderate evidencePotential side effects
- · Mild GI upset
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified Myo-Inositol — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Myo-Inositol third party tested NSF
CapsulesPre-measured Myo-Inositol capsules — easiest for travel and consistent daily dosing without scoops or scales.Myo-Inositol capsules
PowderBulk unflavored Myo-Inositol powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Myo-Inositol powder unflavored
Best sellersMost-purchased Myo-Inositol products on Amazon — a quick way to see what's reviewed widely before you commit.Myo-Inositol best sellerScientific evidence8Show studiesHide studies
Inositol in PCOS
Unfer V, et al.
9 RCTs
Improved ovulation and insulin sensitivity.
PubMed: Myo-Inositol — Improves PCOS ovulation
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PubMed: Myo-Inositol — randomized controlled trial
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PubMed: Myo-Inositol — meta-analysis
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PubMed: Myo-Inositol — pharmacokinetics
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PubMed: Myo-Inositol — safety adverse events
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PubMed: Myo-Inositol — dose response
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Google Scholar: Myo-Inositol — clinical evidence
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Cross-database citation index for Myo-Inositol as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.