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evidence · mechanism · dose
Supplements/Compound

Myo-Inositol

Insulin sensitizer for PCOS and metabolic health.

Women's Health

Overview

Insulin sensitizer for PCOS and metabolic health.

Natural sources
    Common forms

      Mechanism of action

      Acts as insulin second messenger via inositol phosphoglycans.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves PCOS ovulation

        Moderate evidence

        Potential side effects

        Common
        • · Mild GI upset
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            2 g twice daily

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Myo-Inositol
            Amazon
            Wide selection · fast shipping
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            iHerb
            Global delivery · curated brands
            Compound
            Myo-Inositol
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            Meta-analysisEndocr Connect · 2017

            Inositol in PCOS

            Unfer V, et al.

            9 RCTs

            Key findings

            Improved ovulation and insulin sensitivity.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Myo-Inositol — Improves PCOS ovulation

            Live PubMed search

            Live results for "Myo-Inositol Improves PCOS ovulation" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Myo-Inositol and "Improves PCOS ovulation". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Myo-Inositol — randomized controlled trial

            Live PubMed search

            Live results for "Myo-Inositol randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Myo-Inositol and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Myo-Inositol — meta-analysis

            Live PubMed search

            Live results for "Myo-Inositol meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Myo-Inositol and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Myo-Inositol — pharmacokinetics

            Live PubMed search

            Live results for "Myo-Inositol pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Myo-Inositol and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Myo-Inositol — safety adverse events

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            Live results for "Myo-Inositol safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Myo-Inositol — dose response

            Live PubMed search

            Live results for "Myo-Inositol dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Myo-Inositol and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Myo-Inositol — clinical evidence

            Live Scholar search

            Cross-database citation index for Myo-Inositol as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.