Overview
Vaccinium macrocarpon for UTI prevention.
- Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
- Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
- Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Mechanism of action
Proanthocyanidins prevent E. coli adhesion.
- · Proanthocyanidins prevent E
- · coli adhesion
Effects on the body
Organ system effects
Cranberry Extract modulates innate and adaptive immune responses, including cytokine signaling and barrier function.
Cranberry Extract has documented effects on female reproductive endocrinology and cycle regulation.
Evidence-based benefits
Reduces UTI recurrence
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
- ·Autoimmune disease (theoretical immune activation)
- ·Immunosuppressants
Supplement interactions
- Vitamin D3 + K2Foundational immune modulation.
- ZincRequired cofactor for innate and adaptive immune function.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Cranberry for UTI prevention
Jepson RG, et al.
24 RCTs
Reduced UTI risk in women.
PubMed: Cranberry Extract — Reduces UTI recurrence
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PubMed: Cranberry Extract — randomized controlled trial
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PubMed: Cranberry Extract — meta-analysis
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PubMed: Cranberry Extract — dose response
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Google Scholar: Cranberry Extract — clinical evidence
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