Overview
Vitex agnus-castus for PMS.
- Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
- Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
- Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Mechanism of action
Dopaminergic activity reduces prolactin.
- · Dopaminergic activity reduces prolactin
Effects on the body
Organ system effects
Chaste Tree (Vitex) has documented effects on female reproductive endocrinology and cycle regulation.
Evidence-based benefits
Reduces PMS symptoms
Moderate evidencePotential side effects
- · GI upset
- · Headache
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Chaste Tree (Vitex) — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Chaste Tree (Vitex) third party tested NSF
CapsulesPre-measured Chaste Tree (Vitex) capsules — easiest for travel and consistent daily dosing without scoops or scales.Chaste Tree (Vitex) capsules
PowderBulk unflavored Chaste Tree (Vitex) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Chaste Tree (Vitex) powder unflavored
Best sellersMost-purchased Chaste Tree (Vitex) products on Amazon — a quick way to see what's reviewed widely before you commit.Chaste Tree (Vitex) best sellerScientific evidence8Show studiesHide studies
Vitex in PMS
Schellenberg R
170 women
Significant improvement in PMS symptoms.
PubMed: Chaste Tree (Vitex) — Reduces PMS symptoms
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PubMed: Chaste Tree (Vitex) — randomized controlled trial
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Google Scholar: Chaste Tree (Vitex) — clinical evidence
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