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Hormone Balance

General endocrine balancing.

Ranked by evidence strength across reported benefits.

Vitamin#1· strong

Vitamin D3

Steroid hormone precursor regulating ~5% of the human genome — bone, immune, and hormonal health.

Herb#2· strong

Chasteberry (Vitex)

Dopaminergic herb reducing prolactin and improving PMS/luteal phase symptoms.

Mineral#3· strong

Iodine

Halogen essential for thyroid hormone synthesis.

Mineral#4· strong

Selenium-Iodine Synergy (note)

See individual selenium and iodine entries; balance is critical for thyroid health.

Mineral#5· strong

Iodine (Thyroid Optimization)

Essential thyroid hormone substrate — careful dosing required in autoimmunity.

Mineral#6· strong

Potassium Iodide

Standard inorganic iodine — thyroid hormone precursor and radioprotectant.

Herb#7· moderate

Tongkat Ali

Malaysian root extract that frees bound testosterone via SHBG reduction.

Compound#8· moderate

DHEA

Adrenal androgen precursor declining with age; used for adrenal insufficiency and aging.

Compound#9· moderate

DIM (Diindolylmethane)

Cruciferous-derived compound modulating estrogen metabolism toward 2-OH pathway.

Compound#10· moderate

DIM (Diindolylmethane)

Cruciferous-vegetable metabolite that shifts estrogen metabolism toward 2-OH (protective) pathways.

Herb#11· moderate

Chasteberry (Vitex)

Dopaminergic herb that lowers prolactin and supports luteal-phase progesterone.

Mineral#12· moderate

Selenium

Trace mineral essential for glutathione peroxidase and thyroid hormone activation.

Herb#13· moderate

Saw Palmetto

Lipidosterolic extract used for BPH urinary symptoms.

Herb#14· moderate

Stinging Nettle Root

Herbal for BPH and SHBG modulation, often paired with saw palmetto.

Mineral#15· moderate

Selenomethionine

Organic selenium form — preferred for thyroid (Hashimoto's) and antioxidant support.

Mineral#16· moderate

Potassium Iodide

Iodine source for thyroid hormone.

Mineral#17· moderate

Lugol's Iodine

Strong iodine solution.

Mineral#18· moderate

Kelp Iodine

Brown seaweed iodine source.

Mineral#19· moderate

Selenium (Selenomethionine)

Antioxidant trace element for thyroid.

Herb#20· moderate

Chaste Tree (Vitex)

Vitex agnus-castus for PMS.

Compound#21· moderate

Royal Jelly

Queen bee secretion with 10-HDA.

Herb#22· moderate

Tongkat Ali Eurycomanone-Standardized

LJ100 standardized to 22% eurypeptides.

Herb#23· moderate

Stinging Nettle Root

Urtica dioica root for free testosterone.

Mineral#24· moderate

Boron Citrate

Boron for hormone modulation.

Herb#25· moderate

KSM-66 Ashwagandha Thyroid

Ashwagandha for subclinical hypothyroid.

Herb#26· moderate

Bladderwrack

Fucus vesiculosus seaweed for thyroid.

Mineral#27· limited

Boron

Trace mineral implicated in steroid hormone metabolism and bone integrity.

Compound#28· limited

Pregnenolone

Master steroid precursor; small doses studied for cognition and PTSD.

Compound#29· limited

Calcium D-Glucarate

Beta-glucuronidase inhibitor promoting elimination of conjugated hormones/toxins.

Compound#30· limited

Calcium-D-Glucarate

Inhibits β-glucuronidase to support estrogen and toxin elimination via the liver.

Herb#31· limited

Ashwagandha (Thyroid Support)

Supports T4→T3 conversion in subclinical hypothyroid adults.