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evidence · mechanism · dose
Supplements/Mineral

Potassium Iodide

Standard inorganic iodine — thyroid hormone precursor and radioprotectant.

Hormone OptimizationGeneral Wellness

Overview

Standard inorganic iodine — thyroid hormone precursor and radioprotectant.

Natural sources
    Common forms

      Forms & variants of Iodine

      Different chemical forms of Iodine behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Iodine

      Halogen essential for thyroid hormone synthesis.

      Lugol's solution
      Lugol's Iodine

      Combined iodine/iodide solution used historically for thyroid support.

      Mechanism of action

      Iodide is concentrated by thyroid NIS pump and incorporated into thyroglobulin.

      Pathways
      • · Thyroid hormone synthesis

      Effects on the body

      Organ system effects

      Evidence-based benefits

      Prevents iodine deficiency goiter

      Strong evidence

      Potential side effects

      Common
        Rare
        • · Hashimoto flare at supraphysiologic dose
        Serious
        • · Iodine-induced hyperthyroidism

        Drug interactions

        No notable interactions reported.

        Supplement interactions

        Pairs well with

        None listed.

        Avoid combining with

        No specific avoidances listed.

        Dosing & bioavailability

        Typical dose
        150 mcg (RDA)
        Upper safe limit
        1100 mcg/d
        With food?
        Optional

        Where to buy

        Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

        Mineral
        Potassium Io…
        Amazon
        Wide selection · fast shipping
        Mineral
        Potassium Io…
        iHerb
        Global delivery · curated brands
        Mineral
        Potassium Io…
        Thorne
        Practitioner-grade · NSF tested

        Scientific evidence (8)

        Systematic reviewBest Pract Res Clin Endocrinol Metab · 2013

        Potassium iodide for thyroid protection in radiation exposure

        Reiners C, Schneider R

        Review of KI prophylaxis post-Chernobyl/Fukushima.

        Key findings

        Effective in preventing radioactive-iodine thyroid uptake when timed correctly.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Potassium Iodide — Prevents iodine deficiency goiter

        Live PubMed search

        Live results for "Potassium Iodide Prevents iodine deficiency goiter" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Potassium Iodide and "Prevents iodine deficiency goiter". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Potassium Iodide — randomized controlled trial

        Live PubMed search

        Live results for "Potassium Iodide randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Potassium Iodide and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Potassium Iodide — meta-analysis

        Live PubMed search

        Live results for "Potassium Iodide meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Potassium Iodide and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Potassium Iodide — pharmacokinetics

        Live PubMed search

        Live results for "Potassium Iodide pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Potassium Iodide and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Potassium Iodide — safety adverse events

        Live PubMed search

        Live results for "Potassium Iodide safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Potassium Iodide and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Potassium Iodide — dose response

        Live PubMed search

        Live results for "Potassium Iodide dose response" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Potassium Iodide and "dose response". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewGoogle Scholar · 1970

        Google Scholar: Potassium Iodide — clinical evidence

        Live Scholar search

        Cross-database citation index for Potassium Iodide as it relates to "clinical evidence".

        Key findings

        Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

        Open study
        Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.