Overview
Essential thyroid hormone substrate — careful dosing required in autoimmunity.
- Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)
- Fortified foods such as cereals, breads, plant milks, and table salt
- Mineral supplements as chelates, citrates, glycinates, or inorganic salts
- Chelated form (glycinate, bisglycinate, citrate, malate)
- Inorganic salt (oxide, sulfate, chloride)
- Liquid ionic solution
- Topical or transdermal preparation
Mechanism of action
Concentrated by NIS; iodinated tyrosine forms T4/T3.
- · Concentrated by NIS
- · iodinated tyrosine forms T4/T3
Effects on the body
Organ system effects
Evidence-based benefits
Corrects iodine deficiency goiter
Strong evidencePotential side effects
- · Hashimoto flare
- · Iodine-induced hyper/hypothyroidism
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Iodine supplementation in mild-to-moderate deficiency
Pearce EN, et al.
Review of iodine repletion strategies.
Restores thyroid function and prevents goiter.
PubMed: Iodine (Thyroid Optimization) — Corrects iodine deficiency goiter
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Google Scholar: Iodine (Thyroid Optimization) — clinical evidence
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