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evidence · mechanism · dose
Supplements/Herb

Dong Quai

aka Angelica sinensis

TCM herb traditionally used for menstrual and menopausal symptoms.

Women's Health

Overview

TCM herb traditionally used for menstrual and menopausal symptoms.

Natural sources
  • Angelica sinensis root
Common forms
  • Dried root
  • Extract

Mechanism of action

Phytoestrogenic activity disputed; mild antispasmodic.

Pathways
  • · Phytoestrogen (mild)

Effects on the body

Supports
Menstrual regularity (traditional)

Organ system effects

Reproductive

Limited modern evidence.

Evidence-based benefits

Mixed evidence for menopausal symptoms

Limited evidence

Potential side effects

Common
    Rare
    • · Photosensitivity
    Serious

      Drug interactions

      Warfarin
      Significant INR increase.
      severe

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid if you are
      • ·Pregnant or breastfeeding (insufficient safety data)
      • ·Children under 18 (unless directed by a clinician)
      • ·Pregnant or breastfeeding
      Avoid with these conditions
      • ·Hormone-sensitive cancers
      • ·Bleeding disorders
      • ·Heavy menstrual bleeding
      Avoid / monitor with these medications
      • ·Warfarin and anticoagulants
      • ·Hormonal therapies
      Before surgery
      • ·Stop ≥2 weeks before surgery.

      Supplement interactions

      Pairs well with

      None listed.

      Avoid combining with
      • Pregnancy
        Uterine stimulant.
      • Estrogen-sensitive cancers
        Theoretical risk.

      Dosing & bioavailability

      Typical dose
      3–4 g dried root or equivalent

      Where to buy

      Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Herb
      Dong Quai
      Amazon
      Wide selection · fast shipping
      Herb
      Dong Quai
      iHerb
      Global delivery · curated brands
      Herb
      Dong Quai
      Thorne
      Practitioner-grade · NSF tested

      Scientific evidence (8)

      RCTFertil Steril · 1997

      Angelica sinensis for menopausal symptoms

      Hirata JD, et al.

      24-week RCT of dong quai in postmenopausal women.

      Key findings

      No significant benefit vs placebo as monotherapy.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Dong Quai — Mixed evidence for menopausal symptoms

      Live PubMed search

      Live results for "Dong Quai Mixed evidence for menopausal symptoms" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Dong Quai and "Mixed evidence for menopausal symptoms". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Dong Quai — randomized controlled trial

      Live PubMed search

      Live results for "Dong Quai randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Dong Quai and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Dong Quai — meta-analysis

      Live PubMed search

      Live results for "Dong Quai meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Dong Quai and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Dong Quai — pharmacokinetics

      Live PubMed search

      Live results for "Dong Quai pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Dong Quai and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Dong Quai — safety adverse events

      Live PubMed search

      Live results for "Dong Quai safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Dong Quai and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Dong Quai — dose response

      Live PubMed search

      Live results for "Dong Quai dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Dong Quai and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Dong Quai — clinical evidence

      Live Scholar search

      Cross-database citation index for Dong Quai as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.