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Cistanche Tubulosa

Desert plant tonic for libido and cognition.

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Overview

Desert plant tonic for libido and cognition.

Natural sources
  • Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
  • Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
  • Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
Common forms
  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Mechanism of action

Echinacoside and acteoside upregulate testosterone synthesis enzymes and exhibit neuroprotection.

Pathways
  • · Echinacoside
  • · acteoside upregulate testosterone synthesis enzymes
  • · exhibit neuroprotection

Effects on the body

Supports
erectile function in aged rats
Supports
Modest cognitive improvement in mild dementia

Organ system effects

Brain & CNS

Cistanche Tubulosa acts on central nervous system targets implicated in attention, memory, and neuroprotection.

Evidence-based benefits

Improves erectile function in aged rats

Limited evidence

Modest cognitive improvement in mild dementia

Limited evidence

Potential side effects

Common
  • · GI upset
Rare
    Serious

      Drug interactions

      Prescription medications (general)
      Always disclose Cistanche Tubulosa use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
      minor

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid if you are
      • ·Pregnant or breastfeeding (insufficient safety data)
      • ·Children under 18 (unless directed by a clinician)
      Avoid with these conditions
      • ·Hormone-sensitive cancers (breast, prostate, ovarian, uterine)
      Avoid / monitor with these medications
      • ·Hormonal contraceptives, HRT, tamoxifen, aromatase inhibitors

      Supplement interactions

      Pairs well with
      • Omega-3 (EPA/DHA)
        Membrane fluidity and neuronal signaling support.
      • Alpha-GPC or CDP-choline
        Provides choline substrate for acetylcholine synthesis.
      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      300–600 mg
      Best form
      Most evidence is based on the standardized extract capsule form.
      Timing
      Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
      With food?
      With food

      Where to buy

      Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Scientific evidence9Show studies
      RCTJ Alzheimers Dis · 2017

      Cistanche on cognition in mild AD

      Wang T, et al.

      48-week trial in mild-moderate AD patients.

      Key findings

      Improved MMSE and ADAS-cog vs placebo.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Cistanche Tubulosa — Improves erectile function in aged rats

      Live PubMed search

      Live results for "Cistanche Tubulosa Improves erectile function in aged rats" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Cistanche Tubulosa and "Improves erectile function in aged rats". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Cistanche Tubulosa — Modest cognitive improvement in mild dementia

      Live PubMed search

      Live results for "Cistanche Tubulosa Modest cognitive improvement in mild dementia" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Cistanche Tubulosa and "Modest cognitive improvement in mild dementia". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Cistanche Tubulosa — randomized controlled trial

      Live PubMed search

      Live results for "Cistanche Tubulosa randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Cistanche Tubulosa and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Cistanche Tubulosa — meta-analysis

      Live PubMed search

      Live results for "Cistanche Tubulosa meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Cistanche Tubulosa and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Cistanche Tubulosa — pharmacokinetics

      Live PubMed search

      Live results for "Cistanche Tubulosa pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Cistanche Tubulosa and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Cistanche Tubulosa — safety adverse events

      Live PubMed search

      Live results for "Cistanche Tubulosa safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Cistanche Tubulosa and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Cistanche Tubulosa — dose response

      Live PubMed search

      Live results for "Cistanche Tubulosa dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Cistanche Tubulosa and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Cistanche Tubulosa — clinical evidence

      Live Scholar search

      Cross-database citation index for Cistanche Tubulosa as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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