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evidence · mechanism · dose
Supplements/Herb

Panax Ginseng

aka Korean ginseng · Asian ginseng

Adaptogenic ginseng studied for fatigue, cognition, and erectile function.

Energy ProductionBrain & CognitiveLibido & Sexual HealthCortisol Management

Overview

Adaptogenic ginseng studied for fatigue, cognition, and erectile function.

Natural sources
  • Panax ginseng root
Common forms
  • Standardized to ginsenosides (4–7%)
  • Red Korean ginseng

Forms & variants of Panax Ginseng

Different chemical forms of Panax Ginseng behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Cognitive dose
Panax Ginseng (Cognitive)

Asian ginseng (G115) studied for mental performance.

Mechanism of action

Ginsenosides modulate HPA axis, NO synthase, and acetylcholine signaling.

Pathways
  • · NO ↑
  • · HPA modulation
  • · Adaptogenic

Effects on the body

Decreases
Mental fatigue
Supports
Erectile function

Organ system effects

Brain & CNS

Improves working memory and reduces fatigue.

Reproductive

Improves IIEF scores in mild-moderate ED.

Evidence-based benefits

Improves erectile function in mild-moderate ED

Moderate evidence

Reduces cancer-related fatigue

Moderate evidence

Potential side effects

Common
  • · Insomnia (if late)
  • · Headache
Rare
  • · Mastalgia
Serious

    Drug interactions

    Warfarin
    May reduce INR.
    moderate
    MAOIs
    Reported mania/insomnia.
    moderate

    Safety & non-supplemental interactions

    Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

    Avoid if you are
    • ·Pregnant or breastfeeding (insufficient safety data)
    • ·Children under 18 (unless directed by a clinician)
    Avoid / monitor with these medications
    • ·Alcohol, benzodiazepines, opioids, sedating antihistamines (additive CNS depression)

    Supplement interactions

    Pairs well with

    None listed.

    Avoid combining with

    No specific avoidances listed.

    Dosing & bioavailability

    Typical dose
    200–400 mg standardized extract

    Where to buy

    Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

    Herb
    Panax Ginseng
    Amazon
    Wide selection · fast shipping
    Herb
    Panax Ginseng
    iHerb
    Global delivery · curated brands
    Herb
    Panax Ginseng
    Thorne
    Practitioner-grade · NSF tested

    Scientific evidence (9)

    Systematic reviewExamine.com Supplement Database · 2023

    Panax Ginseng: pharmacology, clinical evidence, and safety — narrative review

    Examine.com Research Team

    Curated narrative review of human and preclinical evidence for Panax Ginseng, including mechanism, typical dosing, and safety considerations.

    Key findings

    Best-supported outcome: Improves erectile function in mild-moderate ED (evidence: moderate). Additional outcomes and limitations summarized in the full profile.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Panax Ginseng — Improves erectile function in mild-moderate ED

    Live PubMed search

    Live results for "Panax Ginseng Improves erectile function in mild-moderate ED" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Panax Ginseng and "Improves erectile function in mild-moderate ED". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Panax Ginseng — Reduces cancer-related fatigue

    Live PubMed search

    Live results for "Panax Ginseng Reduces cancer-related fatigue" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Panax Ginseng and "Reduces cancer-related fatigue". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Panax Ginseng — randomized controlled trial

    Live PubMed search

    Live results for "Panax Ginseng randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Panax Ginseng and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Panax Ginseng — meta-analysis

    Live PubMed search

    Live results for "Panax Ginseng meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Panax Ginseng and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Panax Ginseng — pharmacokinetics

    Live PubMed search

    Live results for "Panax Ginseng pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Panax Ginseng and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Panax Ginseng — safety adverse events

    Live PubMed search

    Live results for "Panax Ginseng safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Panax Ginseng and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Panax Ginseng — dose response

    Live PubMed search

    Live results for "Panax Ginseng dose response" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Panax Ginseng and "dose response". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewGoogle Scholar · 1970

    Google Scholar: Panax Ginseng — clinical evidence

    Live Scholar search

    Cross-database citation index for Panax Ginseng as it relates to "clinical evidence".

    Key findings

    Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

    Open study
    Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.