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Power Output

Explosive power and rate of force.

Ranked by evidence strength across reported benefits.

Compound#1· strong

Creatine Monohydrate

The most-studied and effective ergogenic aid — replenishes ATP via the phosphocreatine system.

Mineral#2· strong

Magnesium

Essential cofactor in 300+ enzymatic reactions, from ATP production to muscle relaxation.

Herb#3· strong

Ashwagandha

Adaptogenic herb that down-regulates HPA-axis output — lowers cortisol, supports T in stressed men.

Compound#4· strong

Whey Protein

Fast-digesting complete protein rich in leucine for muscle protein synthesis.

Compound#5· strong

Caffeine

Adenosine antagonist with strong evidence for cognitive and physical performance.

Mineral#6· strong

Magnesium Glycinate

Chelated magnesium bound to glycine — best-tolerated form for sleep, calm, and muscle relaxation.

Amino Acid#7· strong

L-Leucine

Essential BCAA and primary anabolic signaler via mTORC1 activation.

Compound#8· strong

Beetroot Juice

Dietary nitrate source improving NO production, BP, and endurance performance.

Compound#9· strong

Betaine Anhydrous (TMG)

Methyl donor — improves power output and lowers homocysteine.

Compound#10· strong

Creatine Monohydrate

Gold-standard creatine form — the most studied supplement in sports science.

Mineral#11· strong

Sodium

Primary extracellular cation governing plasma volume and nerve conduction.

Amino Acid#12· strong

Beta-Alanine

Carnosine precursor buffering muscle pH during high-intensity work (60–240 sec).

Mineral#13· strong

Electrolyte Blend

Sodium-forward electrolyte mix for endurance, low-carb diets, and rehydration.

Amino Acid#14· strong

Beta-Alanine

Rate-limiting precursor of muscle carnosine — buffers acid during high-intensity work.

Compound#15· strong

Sodium Bicarbonate

Extracellular buffer used for high-intensity exercise capacity.

Amino Acid#16· strong

Essential Amino Acids (EAA)

Full-spectrum EAA blend providing all 9 essentials for MPS.

Compound#17· moderate

Coenzyme Q10

Mitochondrial electron carrier and lipid-soluble antioxidant.

Amino Acid#18· moderate

L-Carnitine

Shuttles long-chain fatty acids into mitochondria for β-oxidation.

Herb#19· moderate

Rhodiola Rosea

Arctic adaptogen — reduces fatigue and improves mental performance under stress.

Amino Acid#20· moderate

L-Arginine

Conditionally essential amino acid and direct nitric oxide precursor.

Compound#21· moderate

Astaxanthin

Algal carotenoid that is the strongest membrane antioxidant; UV and eye protection.

Compound#22· moderate

Bovine Colostrum

First milk rich in IgG, lactoferrin, and growth factors for immune and gut support.

Amino Acid#23· moderate

Citrulline Malate

NO precursor stacked with malate — improves pump and reduces post-workout soreness.

Compound#24· moderate

HMB (β-Hydroxy-β-Methylbutyrate)

Leucine metabolite — anti-catabolic, useful for cutting phases and untrained populations.

Herb#25· moderate

KSM-66 Ashwagandha

Root-only standardized ashwagandha extract — the most-studied form for stress and T-support.

Nootropic#26· moderate

Alpha-GPC

Bioavailable choline source studied for cognition and acute power output.

Amino Acid#27· moderate

Taurine

Conditionally essential amino acid involved in bile salt conjugation, osmoregulation, and cardiac function.

Amino Acid#28· moderate

L-Citrulline

Arginine precursor with superior bioavailability for NO and pump-driven performance.

Amino Acid#29· moderate

BCAAs

Branched-chain amino acids — leucine is the primary mTOR signal for muscle protein synthesis.

Compound#30· moderate

HMB

Leucine metabolite reducing muscle protein breakdown, useful in untrained/elderly populations.

Peptide#31· moderate

Ipamorelin

Selective GH secretagogue researched for muscle and recovery; not FDA approved.

Amino Acid#32· moderate

Taurine

Conditionally essential amino acid with cardiovascular, metabolic, and longevity effects.

Compound#33· moderate

NMN (Nicotinamide Mononucleotide)

Direct NAD+ precursor — popular longevity supplement with growing human data.

Compound#34· moderate

Casein Protein

Slow-digesting milk protein providing sustained amino acid release, popular pre-sleep.

Amino Acid#35· moderate

EAAs (Essential Amino Acids)

All 9 essential amino acids; superior to BCAAs alone for MPS.

Mushroom#36· moderate

Cordyceps

Medicinal fungus studied for aerobic capacity and immune modulation.

Mineral#37· moderate

Magnesium Glycinate

Bisglycinate chelate form of magnesium — gentle, well-absorbed, ideal for sleep.

Compound#38· moderate

Urolithin A

Gut-microbial metabolite of ellagitannins — induces mitophagy.

Amino Acid#39· moderate

L-Carnosine

Histidine dipeptide — anti-glycation and pH buffering.

Herb#40· moderate

Ashwagandha (Strength)

KSM-66 dose for resistance training adaptations.

Compound#41· moderate

Betaine (Strength)

Methyl donor used for power output and body composition.

Mineral#42· moderate

Vanadyl Sulfate

Trace mineral with insulin-mimetic effects studied for T2DM.

Mushroom#43· moderate

Cordyceps CS-4

Standardized cultivated cordyceps for kidney and energy support.

Compound#44· moderate

MK-677 (Ibutamoren) — Ref

Oral ghrelin mimetic that raises GH/IGF-1 (research reference).

Peptide#45· moderate

Ipamorelin (Ref)

Selective GHRP-2 analog with minimal cortisol/prolactin effect.

Compound#46· moderate

Urolithin A (Mitopure)

Gut-derived ellagitannin metabolite that induces mitophagy.

Compound#47· moderate

Creatine (Cognitive Dose)

Higher-dose creatine for cognitive performance under stress.

Compound#48· moderate

Shilajit (Fulvic-Standardized)

Himalayan mineral pitch with fulvic acids studied for testosterone.

Peptide#49· moderate

CJC-1295

GHRH analog with extended half-life.

Compound#50· moderate

BHB Salts (Exogenous Ketones)

Beta-hydroxybutyrate salts for rapid ketosis.

Amino Acid#51· moderate

L-Leucine

Branched-chain amino acid that triggers mTOR.

Mushroom#52· moderate

Cordyceps Militaris

Cordycepin-rich mushroom for energy and exercise.

Herb#53· moderate

Suma Root

Brazilian ginseng adaptogen.

Compound#54· moderate

2S-Hesperidin (Cardiose)

Bioactive isomer of hesperidin.

Compound#55· moderate

Beetroot Nitrate

Inorganic nitrate for NO production.

Amino Acid#56· moderate

EAA Blend (Essential Amino Acids)

Complete essential amino blend.

Amino Acid#57· moderate

BCAA 2:1:1

Leucine:Isoleucine:Valine for muscle.

Amino Acid#58· moderate

Leucine (Mono)

Pure leucine for mTOR.

Amino Acid#59· moderate

L-Valine

BCAA for endurance.

Compound#60· moderate

HMB-Free Acid

Faster-absorbing HMB form.

Compound#61· moderate

Buffered Creatine (Kre-Alkalyn)

pH-buffered creatine.

Compound#62· moderate

Creatine Ethyl Ester

Ester form of creatine.

Fatty Acid#63· moderate

Arachidonic Acid

Omega-6 for muscle inflammation signaling.

Compound#64· moderate

(−)-Epicatechin

Cocoa flavanol for follistatin/myostatin.

Compound#65· moderate

5α-Hydroxy Laxogenin

Plant spirostan for muscle.

Compound#66· moderate

Turkesterone

Ajuga turkestanica ecdysteroid.

Compound#67· moderate

20-Hydroxyecdysone

Spinach ecdysteroid.

Compound#68· moderate

Whey Protein Isolate

Highly bioavailable protein.

Compound#69· moderate

Micellar Casein

Slow-digesting milk protein.

Compound#70· moderate

Egg White Protein

Highest PDCAAS plant-free protein.

Compound#71· moderate

Pea Protein Isolate

Plant-based protein.

Compound#72· moderate

Brown Rice Protein

Hypoallergenic plant protein.

Compound#73· moderate

Hemp Protein

Cannabis sativa seed protein.

Mineral#74· limited

Magnesium Orotate

Magnesium + orotic acid — studied specifically in heart failure and athletic populations.

Herb#75· limited

Fadogia Agrestis

Nigerian shrub — popularized for testosterone support; sparse human data.

Mineral#76· limited

Magnesium Malate

Magnesium + malic acid — favored for daytime energy and fibromyalgia-related fatigue.

Mineral#77· limited

Magnesium Chloride

Topical and oral magnesium with good absorption — commonly used in 'magnesium oil' sprays.

Compound#78· limited

Creatine HCl

Hydrochloride salt of creatine — more water-soluble, marketed for less bloating.

Amino Acid#79· limited

Creatine HCl

Alternative creatine form marketed for higher solubility; efficacy equivalent to monohydrate per gram active creatine.

Nootropic#80· limited

Phenylpiracetam Hydrazide

Hydrazide analog of phenylpiracetam reported to support memory and locomotion.

Compound#81· limited

Deer Antler Velvet

IGF-1-containing traditional preparation marketed for recovery.

Compound#82· limited

Alpha-Ketoglutarate (AKG)

TCA-cycle intermediate studied for healthspan and frailty.

Amino Acid#83· limited

L-Carnosine

Dipeptide that buffers protons and reduces advanced glycation end-products.

Compound#84· limited

Phosphatidic Acid

Phospholipid activator of mTORC1 marketed for hypertrophy.

Compound#85· limited

(-)-Epicatechin

Cocoa flavanol that suppresses myostatin and improves NO.

Compound#86· limited

Ursolic Acid

Apple-peel triterpene with anabolic and lipolytic effects in rodents.

Herb#87· limited

Rhaponticum Carthamoides

Russian adaptogen with ecdysteroid content for performance.

Compound#88· limited

Ecdysterone (Isolated)

Spinach/Rhaponticum-derived steroid with anabolic claims.