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Supplements/Nootropic

Phenylpiracetam Hydrazide

aka Fonturacetam hydrazide

Hydrazide analog of phenylpiracetam reported to support memory and locomotion.

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Overview

Hydrazide analog of phenylpiracetam reported to support memory and locomotion.

Natural sources
  • Manufactured pharmaceutical-grade compound
  • Standardized botanical extract (for plant-derived nootropics)
  • Stack formulations combined with cholinergic or adaptogenic ingredients
Common forms
  • Capsule
  • Powder for stacking
  • Sublingual tablet
  • Liposomal liquid

Mechanism of action

Putative AMPA modulator; precise mechanism uncharacterized in humans.

Pathways
  • · Putative AMPA modulator
  • · precise mechanism uncharacterized in humans

Effects on the body

Supports
Animal models show locomotor enhancement

Organ system effects

Brain & CNS

Phenylpiracetam Hydrazide acts on central nervous system targets implicated in attention, memory, and neuroprotection.

Skeletal Muscle

Phenylpiracetam Hydrazide supports energy delivery, fatigue resistance, or recovery in athletic populations.

Evidence-based benefits

Animal models show locomotor enhancement

Limited evidence

Potential side effects

Common
  • · Irritability
Rare
  • · Tolerance
Serious

    Drug interactions

    Prescription medications (general)
    Always disclose Phenylpiracetam Hydrazide use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
    minor

    Safety & non-supplemental interactions

    Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

    Avoid if you are
    • ·Pregnant or breastfeeding (insufficient safety data)
    • ·Children under 18 (unless directed by a clinician)

    Supplement interactions

    Pairs well with
    • Omega-3 (EPA/DHA)
      Membrane fluidity and neuronal signaling support.
    • Alpha-GPC or CDP-choline
      Provides choline substrate for acetylcholine synthesis.
    Avoid combining with

    No specific avoidances listed.

    Dosing & bioavailability

    Typical dose
    100–200 mg (experimental)
    Best form
    Most evidence is based on the capsule form.
    Timing
    Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
    With food?
    Either with or without food.

    Where to buy

    Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

    Scientific evidence8Show studies
    AnimalEksp Klin Farmakol · 2007

    Phenotropil derivatives in rodents

    Kovalev GI, et al.

    Rodent behavioral panel after phenylpiracetam derivatives.

    Key findings

    Improved learning and locomotor activity vs control.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Phenylpiracetam Hydrazide — Animal models show locomotor enhancement

    Live PubMed search

    Live results for "Phenylpiracetam Hydrazide Animal models show locomotor enhancement" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "Animal models show locomotor enhancement". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Phenylpiracetam Hydrazide — randomized controlled trial

    Live PubMed search

    Live results for "Phenylpiracetam Hydrazide randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Phenylpiracetam Hydrazide — meta-analysis

    Live PubMed search

    Live results for "Phenylpiracetam Hydrazide meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Phenylpiracetam Hydrazide — pharmacokinetics

    Live PubMed search

    Live results for "Phenylpiracetam Hydrazide pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Phenylpiracetam Hydrazide — safety adverse events

    Live PubMed search

    Live results for "Phenylpiracetam Hydrazide safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Phenylpiracetam Hydrazide — dose response

    Live PubMed search

    Live results for "Phenylpiracetam Hydrazide dose response" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "dose response". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewGoogle Scholar · 1970

    Google Scholar: Phenylpiracetam Hydrazide — clinical evidence

    Live Scholar search

    Cross-database citation index for Phenylpiracetam Hydrazide as it relates to "clinical evidence".

    Key findings

    Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

    Open study
    Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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