Overview
NO precursor stacked with malate — improves pump and reduces post-workout soreness.
- Dietary protein from animal sources (meat, fish, eggs, dairy) and plant sources (soy, legumes, grains)
- Free-form amino acid powders and capsules
- Targeted pre-workout, recovery, or sleep formulations
- Free-form crystalline powder
- Capsules or tablets
- Pre-mixed recovery or hydration beverages
- Time-release formulations
Mechanism of action
Citrulline → arginine → NO; malate enters TCA cycle.
- · Citrulline → arginine → NO
- · malate enters TCA cycle
Effects on the body
Organ system effects
Citrulline Malate supports energy delivery, fatigue resistance, or recovery in athletic populations.
Evidence-based benefits
Improves reps to failure
Moderate evidenceReduces DOMS
Moderate evidencePotential side effects
- · GI distress at high dose
Drug interactions
Supplement interactions
- Creatine monohydrateFoundational support for strength, power, and lean mass.
- Whey or EAAsProvides amino acid substrate for muscle protein synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified Citrulline Malate — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Citrulline Malate third party tested NSF
CapsulesPre-measured Citrulline Malate capsules — easiest for travel and consistent daily dosing without scoops or scales.Citrulline Malate capsules
PowderBulk unflavored Citrulline Malate powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Citrulline Malate powder unflavored
Best sellersMost-purchased Citrulline Malate products on Amazon — a quick way to see what's reviewed widely before you commit.Citrulline Malate best sellerScientific evidence9Show studiesHide studies
Citrulline malate on resistance exercise performance
Pérez-Guisado J, Jakeman PM
Crossover trial of 8 g CM before resistance exercise.
Increased reps and reduced soreness.
PubMed: Citrulline Malate — Improves reps to failure
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PubMed: Citrulline Malate — Reduces DOMS
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Google Scholar: Citrulline Malate — clinical evidence
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