Overview
pH-buffered creatine.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Higher pH for stability claim.
- · Higher pH for stability claim
Effects on the body
Organ system effects
Buffered Creatine (Kre-Alkalyn) influences muscle protein synthesis, neuromuscular output, or recovery from exercise.
Evidence-based benefits
Same as monohydrate
Moderate evidencePotential side effects
- · Well tolerated
Drug interactions
Supplement interactions
- Creatine monohydrateFoundational support for strength, power, and lean mass.
- Whey or EAAsProvides amino acid substrate for muscle protein synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Buffered creatine
Jagim AR, et al.
36 men
No advantage over monohydrate.
PubMed: Buffered Creatine (Kre-Alkalyn) — Same as monohydrate
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Google Scholar: Buffered Creatine (Kre-Alkalyn) — clinical evidence
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