Overview
Omega-6 for muscle inflammation signaling.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Eicosanoid precursor; mTOR activator.
- · Eicosanoid precursor
- · mTOR activator
Effects on the body
Organ system effects
Arachidonic Acid influences muscle protein synthesis, neuromuscular output, or recovery from exercise.
Evidence-based benefits
Increases muscle thickness
Moderate evidencePotential side effects
- · Inflammation concerns
Drug interactions
Supplement interactions
- Creatine monohydrateFoundational support for strength, power, and lean mass.
- Whey or EAAsProvides amino acid substrate for muscle protein synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
ARA and resistance training
De Souza EO, et al.
30 men
Increased lean mass.
PubMed: Arachidonic Acid — Increases muscle thickness
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PubMed: Arachidonic Acid — randomized controlled trial
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PubMed: Arachidonic Acid — meta-analysis
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PubMed: Arachidonic Acid — pharmacokinetics
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PubMed: Arachidonic Acid — safety adverse events
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PubMed: Arachidonic Acid — dose response
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Google Scholar: Arachidonic Acid — clinical evidence
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