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Supplements/Fatty Acid

Arachidonic Acid

Omega-6 for muscle inflammation signaling.

Overview

Omega-6 for muscle inflammation signaling.

Natural sources
    Common forms

      Mechanism of action

      Eicosanoid precursor; mTOR activator.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Increases muscle thickness

        Moderate evidence

        Potential side effects

        Common
        • · Inflammation concerns
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            1.5 g

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Scientific evidence (8)

            RCTJ Int Soc Sports Nutr · 2016

            ARA and resistance training

            De Souza EO, et al.

            30 men

            Key findings

            Increased lean mass.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Arachidonic Acid — Increases muscle thickness

            Live PubMed search

            Live results for "Arachidonic Acid Increases muscle thickness" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Arachidonic Acid and "Increases muscle thickness". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Arachidonic Acid — randomized controlled trial

            Live PubMed search

            Live results for "Arachidonic Acid randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Arachidonic Acid and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Arachidonic Acid — meta-analysis

            Live PubMed search

            Live results for "Arachidonic Acid meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Arachidonic Acid and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Arachidonic Acid — pharmacokinetics

            Live PubMed search

            Live results for "Arachidonic Acid pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Arachidonic Acid and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Arachidonic Acid — safety adverse events

            Live PubMed search

            Live results for "Arachidonic Acid safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Arachidonic Acid and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Arachidonic Acid — dose response

            Live PubMed search

            Live results for "Arachidonic Acid dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Arachidonic Acid and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Arachidonic Acid — clinical evidence

            Live Scholar search

            Cross-database citation index for Arachidonic Acid as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.