Overview
Bioactive isomer of hesperidin.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Higher bioavailability; vasoprotective.
- · Higher bioavailability
- · vasoprotective
Effects on the body
Organ system effects
2S-Hesperidin (Cardiose) supports endothelial function, lipid profile, or blood-pressure regulation in cardiovascular trials.
2S-Hesperidin (Cardiose) supports energy delivery, fatigue resistance, or recovery in athletic populations.
Evidence-based benefits
Improves endothelial function
Moderate evidencePotential side effects
- · Well tolerated
Drug interactions
Supplement interactions
- Omega-3Anti-inflammatory cardiovascular synergy.
- CoQ10Supports mitochondrial energetics in cardiac tissue.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified 2S-Hesperidin (Cardiose) — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.2S-Hesperidin (Cardiose) third party tested NSF
CapsulesPre-measured 2S-Hesperidin (Cardiose) capsules — easiest for travel and consistent daily dosing without scoops or scales.2S-Hesperidin (Cardiose) capsules
PowderBulk unflavored 2S-Hesperidin (Cardiose) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.2S-Hesperidin (Cardiose) powder unflavored
Best sellersMost-purchased 2S-Hesperidin (Cardiose) products on Amazon — a quick way to see what's reviewed widely before you commit.2S-Hesperidin (Cardiose) best sellerScientific evidence8Show studiesHide studies
2S-hesperidin and cycling
Martinez-Noguera FJ, et al.
40 cyclists
Improved time-trial performance.
PubMed: 2S-Hesperidin (Cardiose) — Improves endothelial function
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PubMed: 2S-Hesperidin (Cardiose) — randomized controlled trial
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Google Scholar: 2S-Hesperidin (Cardiose) — clinical evidence
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