Overview
Spinach/Rhaponticum-derived steroid with anabolic claims.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Likely ER-β agonism; some evidence for mTOR activation.
- · Likely ER-β agonism
- · some evidence for mTOR activation
Effects on the body
Organ system effects
Ecdysterone (Isolated) influences muscle protein synthesis, neuromuscular output, or recovery from exercise.
Evidence-based benefits
Increases lean mass with resistance training
Limited evidencePotential side effects
- · WADA banned
Drug interactions
Supplement interactions
- Creatine monohydrateFoundational support for strength, power, and lean mass.
- Whey or EAAsProvides amino acid substrate for muscle protein synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Ecdysterone in athletes
Parr MK, et al.
Trial supplementing trained athletes.
Anabolic effects without androgen-receptor binding.
PubMed: Ecdysterone (Isolated) — Increases lean mass with resistance training
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PubMed: Ecdysterone (Isolated) — randomized controlled trial
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PubMed: Ecdysterone (Isolated) — meta-analysis
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PubMed: Ecdysterone (Isolated) — pharmacokinetics
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PubMed: Ecdysterone (Isolated) — dose response
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Google Scholar: Ecdysterone (Isolated) — clinical evidence
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