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evidence · mechanism · dose
Supplements/Mineral

Vanadyl Sulfate

Trace mineral with insulin-mimetic effects studied for T2DM.

Blood Sugar ManagementMuscle Growth

Overview

Trace mineral with insulin-mimetic effects studied for T2DM.

Natural sources
    Common forms

      Mechanism of action

      Inhibits phosphotyrosine phosphatases, prolonging insulin receptor activation.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Lowers fasting glucose in T2DM (short-term)

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        Rare
        • · Green tongue
        Serious
        • · Long-term safety unknown

        Drug interactions

        No notable interactions reported.

        Supplement interactions

        Pairs well with

        None listed.

        Avoid combining with

        No specific avoidances listed.

        Dosing & bioavailability

        Typical dose
        50–100 mg (research)
        With food?
        With food

        Where to buy

        Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

        Mineral
        Vanadyl Sulf…
        Amazon
        Wide selection · fast shipping
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        iHerb
        Global delivery · curated brands
        Mineral
        Vanadyl Sulf…
        Thorne
        Practitioner-grade · NSF tested

        Scientific evidence (8)

        RCTMetabolism · 2000

        Vanadyl sulfate in T2DM

        Goldfine AB, et al.

        6-week trial in 11 T2DM patients.

        Key findings

        Reduced fasting glucose and HbA1c.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Vanadyl Sulfate — Lowers fasting glucose in T2DM

        Live PubMed search

        Live results for "Vanadyl Sulfate Lowers fasting glucose in T2DM" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Vanadyl Sulfate and "Lowers fasting glucose in T2DM". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Vanadyl Sulfate — randomized controlled trial

        Live PubMed search

        Live results for "Vanadyl Sulfate randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Vanadyl Sulfate and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Vanadyl Sulfate — meta-analysis

        Live PubMed search

        Live results for "Vanadyl Sulfate meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Vanadyl Sulfate and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Vanadyl Sulfate — pharmacokinetics

        Live PubMed search

        Live results for "Vanadyl Sulfate pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Vanadyl Sulfate and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Vanadyl Sulfate — safety adverse events

        Live PubMed search

        Live results for "Vanadyl Sulfate safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Vanadyl Sulfate and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Vanadyl Sulfate — dose response

        Live PubMed search

        Live results for "Vanadyl Sulfate dose response" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Vanadyl Sulfate and "dose response". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewGoogle Scholar · 1970

        Google Scholar: Vanadyl Sulfate — clinical evidence

        Live Scholar search

        Cross-database citation index for Vanadyl Sulfate as it relates to "clinical evidence".

        Key findings

        Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

        Open study
        Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.