Overview
Pure leucine for mTOR.
- Dietary protein from animal sources (meat, fish, eggs, dairy) and plant sources (soy, legumes, grains)
- Free-form amino acid powders and capsules
- Targeted pre-workout, recovery, or sleep formulations
- Free-form crystalline powder
- Capsules or tablets
- Pre-mixed recovery or hydration beverages
- Time-release formulations
Mechanism of action
Anabolic trigger.
- · Anabolic trigger
Effects on the body
Organ system effects
Leucine (Mono) influences muscle protein synthesis, neuromuscular output, or recovery from exercise.
Evidence-based benefits
Stimulates MPS
Moderate evidencePotential side effects
- · Well tolerated
Drug interactions
Supplement interactions
- Creatine monohydrateFoundational support for strength, power, and lean mass.
- Whey or EAAsProvides amino acid substrate for muscle protein synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Leucine for sarcopenia
Borack MS, Volpi E
Clinical review
Effective for elderly muscle preservation.
PubMed: Leucine (Mono) — Stimulates MPS
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PubMed: Leucine (Mono) — randomized controlled trial
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PubMed: Leucine (Mono) — meta-analysis
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PubMed: Leucine (Mono) — pharmacokinetics
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PubMed: Leucine (Mono) — safety adverse events
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PubMed: Leucine (Mono) — dose response
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Google Scholar: Leucine (Mono) — clinical evidence
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