Overview
First milk rich in IgG, lactoferrin, and growth factors for immune and gut support.
- Bovine first-milk colostrum
- Standardized IgG colostrum
Mechanism of action
Provides passive immunity (IgG), lactoferrin (antimicrobial), and IGF-1.
- · Passive immunity
- · Gut barrier
Effects on the body
Organ system effects
Reduces NSAID-induced gut permeability.
Evidence-based benefits
Reduces URI incidence in athletes
Moderate evidenceReduces NSAID-induced gut hyperpermeability
Moderate evidencePotential side effects
- · Bloating
- · Dairy allergy
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Autoimmune disease (theoretical immune activation)
- ·Immunosuppressants
Supplement interactions
- Vitamin D3 + K2Foundational immune modulation.
- ZincRequired cofactor for innate and adaptive immune function.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Scientific evidence9Show studiesHide studies
Bovine colostrum and upper respiratory infections
Patel K, Rana R
RCT of colostrum in children for URTI prevention.
Reduced URTI episodes and severity.
PubMed: Bovine Colostrum — Reduces URI incidence in athletes
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PubMed: Bovine Colostrum — Reduces NSAID-induced gut hyperpermeability
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PubMed: Bovine Colostrum — randomized controlled trial
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PubMed: Bovine Colostrum — meta-analysis
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PubMed: Bovine Colostrum — pharmacokinetics
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PubMed: Bovine Colostrum — safety adverse events
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PubMed: Bovine Colostrum — dose response
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Google Scholar: Bovine Colostrum — clinical evidence
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