Overview
Apple-peel triterpene with anabolic and lipolytic effects in rodents.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Suppresses atrophy genes and stimulates IGF-1/Akt signaling.
- · Suppresses atrophy genes
- · stimulates IGF-1/Akt signaling
Effects on the body
Organ system effects
Ursolic Acid influences muscle protein synthesis, neuromuscular output, or recovery from exercise.
Evidence-based benefits
Increases lean mass in untrained mice
Limited evidencePotential side effects
- · GI upset
Drug interactions
Supplement interactions
- Creatine monohydrateFoundational support for strength, power, and lean mass.
- Whey or EAAsProvides amino acid substrate for muscle protein synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Ursolic Acid — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Ursolic Acid third party tested NSF
CapsulesPre-measured Ursolic Acid capsules — easiest for travel and consistent daily dosing without scoops or scales.Ursolic Acid capsules
PowderBulk unflavored Ursolic Acid powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Ursolic Acid powder unflavored
Best sellersMost-purchased Ursolic Acid products on Amazon — a quick way to see what's reviewed widely before you commit.Ursolic Acid best sellerScientific evidence8Show studiesHide studies
Ursolic acid in mice
Kunkel SD, et al.
Mice given ursolic acid + atrophic insult.
Reduced muscle atrophy and improved glucose tolerance.
PubMed: Ursolic Acid — Increases lean mass in untrained mice
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PubMed: Ursolic Acid — randomized controlled trial
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PubMed: Ursolic Acid — meta-analysis
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PubMed: Ursolic Acid — pharmacokinetics
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PubMed: Ursolic Acid — dose response
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Google Scholar: Ursolic Acid — clinical evidence
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