Hormonal Acne
Androgen and sebum modulation for skin.
Ranked by evidence strength across reported benefits.
Vitamin D3
Steroid hormone precursor regulating ~5% of the human genome — bone, immune, and hormonal health.
Vitamin A (Retinol)
Fat-soluble vitamin essential for vision, immune function, and epithelial integrity.
Vitamin B3 (Niacin)
NAD+ precursor; nicotinic acid form lowers LDL and raises HDL.
Vitamin C
Water-soluble antioxidant, collagen cofactor, and immune supporter.
Chasteberry (Vitex)
Dopaminergic herb reducing prolactin and improving PMS/luteal phase symptoms.
Glycine
Inhibitory amino acid that improves sleep quality, glycemic control, and collagen synthesis.
Biotin (B7)
Coenzyme for carboxylases — popular for hair and nails despite weak data outside true deficiency.
Iodine
Halogen essential for thyroid hormone synthesis.
Copper
Trace mineral cofactor for ceruloplasmin and connective tissue crosslinking.
Selenium-Iodine Synergy (note)
See individual selenium and iodine entries; balance is critical for thyroid health.
Iodine (Thyroid Optimization)
Essential thyroid hormone substrate — careful dosing required in autoimmunity.
Potassium Iodide
Standard inorganic iodine — thyroid hormone precursor and radioprotectant.
Gotu Kola (Extra)
Standardized triterpenes for venous insufficiency and skin healing.
Marine Collagen (Extra)
Fish-derived type I collagen with high digestibility.
Copper Bisglycinate
Chelated copper used to balance high-dose zinc supplementation.
Tongkat Ali
Malaysian root extract that frees bound testosterone via SHBG reduction.
Zinc
Cofactor for ~300 enzymes — critical for testosterone, immune function, and DNA synthesis.
Glycine
Inhibitory neurotransmitter that improves sleep quality and supports collagen synthesis.
Vitamin E
Primary lipid-phase antioxidant protecting membrane PUFAs.
Collagen Peptides
Hydrolyzed protein supplying glycine, proline, and hydroxyproline for connective tissue.
Hyaluronic Acid
Glycosaminoglycan supporting skin hydration and joint lubrication.
DHEA
Adrenal androgen precursor declining with age; used for adrenal insufficiency and aging.
Astaxanthin
Algal carotenoid that is the strongest membrane antioxidant; UV and eye protection.
Verisol® Collagen Peptides
Specific bovine peptide blend marketed for skin and cellulite.
Astaxanthin (Eye dose)
Carotenoid that crosses BBB and accumulates in ciliary body.
Glutathione
Master intracellular antioxidant; oral bioavailability depends on form.
Gotu Kola
Adaptogen used for cognitive support, anxiety, and wound healing.
DIM (Diindolylmethane)
Cruciferous-derived compound modulating estrogen metabolism toward 2-OH pathway.
MSM (Methylsulfonylmethane)
Bioavailable sulfur donor for joints, skin, and hair-keratin synthesis.
Marine Collagen Peptides
Hydrolyzed fish collagen — supplies glycine, proline, and bioactive di/tripeptides for skin and hair.
DIM (Diindolylmethane)
Cruciferous-vegetable metabolite that shifts estrogen metabolism toward 2-OH (protective) pathways.
Niacinamide
Non-flushing B3 — used for deficiency, skin health, and at high doses in dermatology.
Biotin (Hair Dose)
B-vitamin used cosmetically for hair and nail growth.
Selenium
Trace mineral essential for glutathione peroxidase and thyroid hormone activation.
Saw Palmetto
Lipidosterolic extract used for BPH urinary symptoms.
Stinging Nettle Root
Herbal for BPH and SHBG modulation, often paired with saw palmetto.
Spearmint Tea
Used for hirsutism in PCOS via mild anti-androgen effect.
GHK-Cu (Copper Peptide)
Copper-binding tripeptide used topically for skin remodeling.
Selenomethionine
Organic selenium form — preferred for thyroid (Hashimoto's) and antioxidant support.
Tocotrienols (Skin/Aging)
Vitamin E isoforms with 40–60× higher antioxidant power than tocopherols.
Centella asiatica (Skin)
Standardized titrated extract for scars and venous skin changes.
Glycine (Collagen Stack)
Free-form glycine paired with collagen for connective tissue synthesis.
Zinc Bisglycinate (High-Bio)
Chelated zinc with superior absorption and tolerability.
Choline-Stabilized Orthosilicic Acid (ch-OSA)
Highly bioavailable silica for hair, skin, and bone.
Centella Triterpene Fraction
Standardized madecassoside/asiaticoside for skin and venous health.
TB-500 (Thymosin Beta-4)
Synthetic thymosin fragment for tissue repair.
Squalene
Olive oil/shark liver lipid antioxidant.
L-Lysine
Essential amino acid for collagen and HSV prevention.
Bamboo Silica
Plant-based silicon for skin and bones.
Choline-Stabilized OSA
Bioavailable silicon form.
Astaxanthin (Haematococcus)
Algae carotenoid antioxidant.
Tremella Fuciformis
Snow fungus for skin hydration.
DMAE (Dimethylaminoethanol)
Choline analog for cognition.
Type III Collagen
Skin and vascular collagen.
Marine Collagen Peptides
Fish-derived collagen.
Bovine Collagen Peptides
Cow-derived collagen hydrolysate.
Hyaluronic Acid (Oral)
Oral HA for skin and joints.
OptiMSM
Distilled MSM for joints.
Biotin (High-Dose)
High-dose for MS and hair.
MSM (Methylsulfonylmethane)
Organic sulfur for joints and skin.
Grape Seed Extract
Vitis vinifera procyanidins.
Manuka Honey
Leptospermum honey with MGO.
Liposomal Vitamin C
Phospholipid-encapsulated vitamin C.
Ascorbyl Palmitate
Fat-soluble vitamin C ester.
Evening Primrose Oil
GLA omega-6 for skin and PMS.
Borage Oil
Highest GLA content.
Blackcurrant Seed Oil
GLA + ALA omega-3/6.
Hemp Seed Oil
3:1 omega-6 to omega-3 ratio.
Vitamin B7 (Biotin)
Carboxylase cofactor marketed for hair, skin, and nail support.
Boron
Trace mineral implicated in steroid hormone metabolism and bone integrity.
Evening Primrose Oil
Omega-6 source rich in GLA, used for atopic dermatitis and cyclical breast pain.
Vitamin B5 (Pantothenic acid)
Component of coenzyme A, central to fatty acid and acetylcholine synthesis.
Silica (Silicon)
Trace element involved in collagen and connective tissue crosslinking.
Pregnenolone
Master steroid precursor; small doses studied for cognition and PTSD.
Calcium D-Glucarate
Beta-glucuronidase inhibitor promoting elimination of conjugated hormones/toxins.
Horsetail Extract
Silica-rich herb traditionally used for hair, nail, and connective tissue support.
Calcium-D-Glucarate
Inhibits β-glucuronidase to support estrogen and toxin elimination via the liver.
Ashwagandha (Thyroid Support)
Supports T4→T3 conversion in subclinical hypothyroid adults.
Zinc Picolinate
Zinc chelated to picolinic acid — one of the most bioavailable oral forms.
Zinc Bisglycinate
Glycine-chelated zinc — high absorption and very gentle on the stomach.
Biotinyl Tripeptide-1 (Procapil)
Topical peptide complex marketed for hair anchoring.