Overview
Synthetic thymosin fragment for tissue repair.
- Synthetic peptide manufactured to pharmaceutical or research-grade purity
- Subcutaneous injection, sublingual, or oral preparation depending on bioavailability
- Compounded by a licensed pharmacy for clinical use
- Subcutaneous injection
- Oral or sublingual lozenge
- Nasal spray
- Compounded topical
Mechanism of action
Sequesters G-actin, promotes angiogenesis and cell migration.
- · Sequesters G-actin, promotes angiogenesis
- · cell migration
Effects on the body
Organ system effects
TB-500 (Thymosin Beta-4) supports collagen synthesis, antioxidant defense, or barrier function in skin and integumentary tissues.
Evidence-based benefits
Accelerates wound healing
Moderate evidencePotential side effects
- · Injection site pain
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
- ·Most research peptides are not FDA-approved for human use outside investigational protocols.
Supplement interactions
- Collagen peptidesProvides amino acid substrate for connective tissue synthesis.
- Vitamin CRequired cofactor for collagen hydroxylation.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Thymosin beta-4 in wound healing
Malinda KM, et al.
Rat wound model
Accelerated wound closure 42%.
PubMed: TB-500 (Thymosin Beta-4) — Accelerates wound healing
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