Overview
Standardized triterpenes for venous insufficiency and skin healing.
- Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
- Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
- Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Forms & variants of Gotu Kola
Different chemical forms of Gotu Kola behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Asiaticoside and madecassoside upregulate collagen and capillary integrity.
- · Asiaticoside
- · madecassoside upregulate collagen
- · capillary integrity
Effects on the body
Organ system effects
Gotu Kola (Extra) supports collagen synthesis, antioxidant defense, or barrier function in skin and integumentary tissues.
Evidence-based benefits
Reduces chronic venous insufficiency symptoms
Strong evidencePotential side effects
- · Skin irritation (topical)
- · Hepatotoxicity (rare)
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- Collagen peptidesProvides amino acid substrate for connective tissue synthesis.
- Vitamin CRequired cofactor for collagen hydroxylation.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Gotu Kola (Extra) — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Gotu Kola (Extra) third party tested NSF
CapsulesPre-measured Gotu Kola (Extra) capsules — easiest for travel and consistent daily dosing without scoops or scales.Gotu Kola (Extra) capsules
PowderBulk unflavored Gotu Kola (Extra) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Gotu Kola (Extra) powder unflavored
Best sellersMost-purchased Gotu Kola (Extra) products on Amazon — a quick way to see what's reviewed widely before you commit.Gotu Kola (Extra) best sellerScientific evidence8Show studiesHide studies
TECA for chronic venous insufficiency
Pointel JP, et al.
DB-RCT in 94 patients with CVI.
Significantly improved symptoms vs placebo over 2 months.
PubMed: Gotu Kola (Extra) — Reduces chronic venous insufficiency symptoms
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