Overview
B-vitamin used cosmetically for hair and nail growth.
- Whole-food sources (animal products for fat-soluble and B-complex vitamins; produce for water-soluble vitamins)
- Fortified foods (cereals, dairy, plant milks, nutritional yeast)
- Multivitamins or stand-alone supplements in synthetic or food-derived form
- Capsule or softgel
- Sublingual tablet or liquid
- Methylated active form for sensitive individuals
- Multivitamin matrix
Forms & variants of Biotin (B7)
Different chemical forms of Biotin (B7) behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Cofactor for carboxylase enzymes; influences keratin gene expression.
- · Cofactor for carboxylase enzymes
- · influences keratin gene expression
Effects on the body
Organ system effects
Biotin (Hair Dose) supports collagen synthesis, antioxidant defense, or barrier function in skin and integumentary tissues.
Evidence-based benefits
Improves brittle nails
Moderate evidenceHair benefits only in deficiency
Limited evidencePotential side effects
- · Acne with very high dose
- · Interferes with thyroid, troponin labs
Drug interactions
Supplement interactions
- Collagen peptidesProvides amino acid substrate for connective tissue synthesis.
- Vitamin CRequired cofactor for collagen hydroxylation.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence9Show studiesHide studies
Biotin for brittle nails
Hochman LG, et al.
Open trial in 35 patients with brittle nails.
2.5 mg/day biotin increased nail thickness by 25% on average.
PubMed: Biotin (Hair Dose) — Improves brittle nails
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PubMed: Biotin (Hair Dose) — Hair benefits only in deficiency
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PubMed: Biotin (Hair Dose) — randomized controlled trial
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PubMed: Biotin (Hair Dose) — meta-analysis
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PubMed: Biotin (Hair Dose) — pharmacokinetics
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PubMed: Biotin (Hair Dose) — dose response
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