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evidence · mechanism · dose
Supplements/Vitamin

Biotin (B7)

aka Vitamin B7 · Vitamin H

Coenzyme for carboxylases — popular for hair and nails despite weak data outside true deficiency.

Hair SupportSkin, Hair & NailsGeneral Wellness

Overview

Coenzyme for carboxylases — popular for hair and nails despite weak data outside true deficiency.

Natural sources
    Common forms

      Forms & variants of Biotin (B7)

      Different chemical forms of Biotin (B7) behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      High-dose hair
      Biotin (Hair Dose)

      B-vitamin used cosmetically for hair and nail growth.

      Mechanism of action

      Cofactor for 5 carboxylases involved in gluconeogenesis, fatty acid synthesis, and amino acid metabolism.

      Pathways
      • · Carboxylase activity
      • · Keratin substrate availability

      Effects on the body

      Organ system effects

      Evidence-based benefits

      Reverses hair/nail issues in biotin deficiency

      Strong evidence

      Improves hair growth in non-deficient adults

      Limited evidence

      Potential side effects

      Common
        Rare
        • · Acne flare
        Serious
        • · Falsely alters thyroid/troponin lab assays at high dose

        Drug interactions

        Thyroid/troponin lab tests
        Hold 48h before bloodwork.
        moderate

        Supplement interactions

        Pairs well with

        None listed.

        Avoid combining with

        No specific avoidances listed.

        Dosing & bioavailability

        Typical dose
        30 mcg (RDA)
        Study range
        2,500–10,000 mcg in hair use
        With food?
        Optional

        Where to buy

        Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

        Vitamin
        Biotin (B7)
        Amazon
        Wide selection · fast shipping
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        Biotin (B7)
        iHerb
        Global delivery · curated brands
        Vitamin
        Biotin (B7)
        Thorne
        Practitioner-grade · NSF tested

        Scientific evidence (9)

        Systematic reviewSkin Appendage Disord · 2017

        Biotin for hair and nail growth

        Patel DP, et al.

        Review of biotin trials in hair/nail disorders.

        Key findings

        Benefits limited to documented biotin deficiency.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Biotin (B7) — Reverses hair/nail issues in biotin deficiency

        Live PubMed search

        Live results for "Biotin (B7) Reverses hair/nail issues in biotin deficiency" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Biotin (B7) and "Reverses hair/nail issues in biotin deficiency". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Biotin (B7) — Improves hair growth in non-deficient adults

        Live PubMed search

        Live results for "Biotin (B7) Improves hair growth in non-deficient adults" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Biotin (B7) and "Improves hair growth in non-deficient adults". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Biotin (B7) — randomized controlled trial

        Live PubMed search

        Live results for "Biotin (B7) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Biotin (B7) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Biotin (B7) — meta-analysis

        Live PubMed search

        Live results for "Biotin (B7) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Biotin (B7) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Biotin (B7) — pharmacokinetics

        Live PubMed search

        Live results for "Biotin (B7) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Biotin (B7) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Biotin (B7) — safety adverse events

        Live PubMed search

        Live results for "Biotin (B7) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Biotin (B7) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Biotin (B7) — dose response

        Live PubMed search

        Live results for "Biotin (B7) dose response" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Biotin (B7) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewGoogle Scholar · 1970

        Google Scholar: Biotin (B7) — clinical evidence

        Live Scholar search

        Cross-database citation index for Biotin (B7) as it relates to "clinical evidence".

        Key findings

        Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

        Open study
        Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.