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evidence · mechanism · dose
Supplements/Compound

Astaxanthin (Eye dose)

Carotenoid that crosses BBB and accumulates in ciliary body.

Eye HealthSkin, Hair & NailsHealthy Aging

Overview

Carotenoid that crosses BBB and accumulates in ciliary body.

Natural sources
    Common forms

      Forms & variants of Astaxanthin

      Different chemical forms of Astaxanthin behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Astaxanthin

      Algae-derived xanthophyll — most potent natural antioxidant; UV/eye/skin support.

      Mechanism of action

      Spans cell membrane to quench ROS at both faces; modulates NF-κB.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces eye strain symptoms

        Moderate evidence

        Improves skin elasticity

        Moderate evidence

        Potential side effects

        Common
        • · Orange skin tinge at high dose
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            6–12 mg
            With food?
            With fat

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Astaxanthin …
            Amazon
            Wide selection · fast shipping
            Compound
            Astaxanthin …
            iHerb
            Global delivery · curated brands
            Compound
            Astaxanthin …
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (9)

            RCTJ Trad Med · 2002

            Astaxanthin on eye accommodation

            Nagaki Y, et al.

            4-week DB-RCT in 26 VDU workers.

            Key findings

            Reduced eye fatigue and improved accommodation amplitude.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Astaxanthin (Eye dose) — Reduces eye strain symptoms

            Live PubMed search

            Live results for "Astaxanthin (Eye dose) Reduces eye strain symptoms" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Astaxanthin (Eye dose) and "Reduces eye strain symptoms". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Astaxanthin (Eye dose) — Improves skin elasticity

            Live PubMed search

            Live results for "Astaxanthin (Eye dose) Improves skin elasticity" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Astaxanthin (Eye dose) and "Improves skin elasticity". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Astaxanthin (Eye dose) — randomized controlled trial

            Live PubMed search

            Live results for "Astaxanthin (Eye dose) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Astaxanthin (Eye dose) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Astaxanthin (Eye dose) — meta-analysis

            Live PubMed search

            Live results for "Astaxanthin (Eye dose) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Astaxanthin (Eye dose) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Astaxanthin (Eye dose) — pharmacokinetics

            Live PubMed search

            Live results for "Astaxanthin (Eye dose) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Astaxanthin (Eye dose) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Astaxanthin (Eye dose) — safety adverse events

            Live PubMed search

            Live results for "Astaxanthin (Eye dose) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Astaxanthin (Eye dose) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Astaxanthin (Eye dose) — dose response

            Live PubMed search

            Live results for "Astaxanthin (Eye dose) dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Astaxanthin (Eye dose) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Astaxanthin (Eye dose) — clinical evidence

            Live Scholar search

            Cross-database citation index for Astaxanthin (Eye dose) as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.