Overview
Carotenoid that crosses BBB and accumulates in ciliary body.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Forms & variants of Astaxanthin
Different chemical forms of Astaxanthin behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Spans cell membrane to quench ROS at both faces; modulates NF-κB.
- · Spans cell membrane to quench ROS at both faces
- · modulates NF-κB
Effects on the body
Organ system effects
Astaxanthin (Eye dose) concentrates in ocular tissues (macula, retina, lens) where it contributes to photoprotection or antioxidant defense.
Astaxanthin (Eye dose) supports collagen synthesis, antioxidant defense, or barrier function in skin and integumentary tissues.
Astaxanthin (Eye dose) acts on hallmarks of aging including oxidative stress, mitochondrial dysfunction, and senescence signaling.
Evidence-based benefits
Reduces eye strain symptoms
Moderate evidenceImproves skin elasticity
Moderate evidencePotential side effects
- · Orange skin tinge at high dose
Drug interactions
Supplement interactions
- Collagen peptidesProvides amino acid substrate for connective tissue synthesis.
- Vitamin CRequired cofactor for collagen hydroxylation.
- NAD+ precursor (NMN or NR)Complementary mitochondrial and sirtuin support.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence9Show studiesHide studies
Astaxanthin on eye accommodation
Nagaki Y, et al.
4-week DB-RCT in 26 VDU workers.
Reduced eye fatigue and improved accommodation amplitude.
PubMed: Astaxanthin (Eye dose) — Reduces eye strain symptoms
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PubMed: Astaxanthin (Eye dose) — Improves skin elasticity
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PubMed: Astaxanthin (Eye dose) — randomized controlled trial
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PubMed: Astaxanthin (Eye dose) — meta-analysis
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PubMed: Astaxanthin (Eye dose) — pharmacokinetics
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PubMed: Astaxanthin (Eye dose) — safety adverse events
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PubMed: Astaxanthin (Eye dose) — dose response
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Google Scholar: Astaxanthin (Eye dose) — clinical evidence
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Cross-database citation index for Astaxanthin (Eye dose) as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.