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evidence · mechanism · dose
Supplements/Mineral

Choline-Stabilized Orthosilicic Acid (ch-OSA)

Highly bioavailable silica for hair, skin, and bone.

Skin, Hair & NailsBone Health

Overview

Highly bioavailable silica for hair, skin, and bone.

Natural sources
    Common forms

      Forms & variants of Silica (Silicon)

      Different chemical forms of Silica (Silicon) behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Silica (Silicon)

      Trace element involved in collagen and connective tissue crosslinking.

      Mechanism of action

      Silicon supports collagen cross-linking and osteoblast activity.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves hair strength and skin elasticity

        Moderate evidence

        Potential side effects

        Common
          Rare
            Serious

              Drug interactions

              No notable interactions reported.

              Supplement interactions

              Pairs well with

              None listed.

              Avoid combining with

              No specific avoidances listed.

              Dosing & bioavailability

              Typical dose
              10 mg silicon/day
              With food?
              Either

              Where to buy

              Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

              Mineral
              Choline-Stab…
              Amazon
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              iHerb
              Global delivery · curated brands
              Mineral
              Choline-Stab…
              Thorne
              Practitioner-grade · NSF tested

              Scientific evidence (8)

              RCTArch Dermatol Res · 2007

              ch-OSA on hair and skin

              Wickett RR, et al.

              9-month DB-RCT in 48 women with fine hair.

              Key findings

              Significantly increased hair tensile strength vs placebo.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — Improves hair strength and skin elasticity

              Live PubMed search

              Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) Improves hair strength and skin elasticity" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "Improves hair strength and skin elasticity". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — randomized controlled trial

              Live PubMed search

              Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — meta-analysis

              Live PubMed search

              Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — pharmacokinetics

              Live PubMed search

              Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — safety adverse events

              Live PubMed search

              Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewPubMed (NLM) · 1970

              PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — dose response

              Live PubMed search

              Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) dose response" across the PubMed/MEDLINE peer-reviewed index.

              Key findings

              Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

              Open study
              Systematic reviewGoogle Scholar · 1970

              Google Scholar: Choline-Stabilized Orthosilicic Acid (ch-OSA) — clinical evidence

              Live Scholar search

              Cross-database citation index for Choline-Stabilized Orthosilicic Acid (ch-OSA) as it relates to "clinical evidence".

              Key findings

              Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

              Open study
              Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.