Overview
Highly bioavailable silica for hair, skin, and bone.
- Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)
- Fortified foods such as cereals, breads, plant milks, and table salt
- Mineral supplements as chelates, citrates, glycinates, or inorganic salts
- Chelated form (glycinate, bisglycinate, citrate, malate)
- Inorganic salt (oxide, sulfate, chloride)
- Liquid ionic solution
- Topical or transdermal preparation
Forms & variants of Silica (Silicon)
Different chemical forms of Silica (Silicon) behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Silicon supports collagen cross-linking and osteoblast activity.
- · Silicon supports collagen cross-linking
- · osteoblast activity
Effects on the body
Organ system effects
Choline-Stabilized Orthosilicic Acid (ch-OSA) supports collagen synthesis, antioxidant defense, or barrier function in skin and integumentary tissues.
Choline-Stabilized Orthosilicic Acid (ch-OSA) contributes to bone mineralization, osteoblast activity, or calcium-phosphate homeostasis.
Evidence-based benefits
Improves hair strength and skin elasticity
Moderate evidencePotential side effects
- · Choline-Stabilized Orthosilicic Acid (ch-OSA) is generally well-tolerated at evidence-based doses
- · Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
- · Headache or transient fatigue reported by a small fraction of users
- · Allergic or hypersensitivity reaction (rash, itching, swelling)
- · Sleep disturbance if taken late in the day
- · Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing
Drug interactions
Supplement interactions
- Collagen peptidesProvides amino acid substrate for connective tissue synthesis.
- Vitamin CRequired cofactor for collagen hydroxylation.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified Choline-Stabilized Orthosilicic Acid (ch-OSA) — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Choline-Stabilized Orthosilicic Acid (ch-OSA) third party tested NSF
CapsulesPre-measured Choline-Stabilized Orthosilicic Acid (ch-OSA) capsules — easiest for travel and consistent daily dosing without scoops or scales.Choline-Stabilized Orthosilicic Acid (ch-OSA) capsules
PowderBulk unflavored Choline-Stabilized Orthosilicic Acid (ch-OSA) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Choline-Stabilized Orthosilicic Acid (ch-OSA) powder unflavored
Best sellersMost-purchased Choline-Stabilized Orthosilicic Acid (ch-OSA) products on Amazon — a quick way to see what's reviewed widely before you commit.Choline-Stabilized Orthosilicic Acid (ch-OSA) best sellerScientific evidence8Show studiesHide studies
ch-OSA on hair and skin
Wickett RR, et al.
9-month DB-RCT in 48 women with fine hair.
Significantly increased hair tensile strength vs placebo.
PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — Improves hair strength and skin elasticity
Live PubMed search
Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) Improves hair strength and skin elasticity" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "Improves hair strength and skin elasticity". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — randomized controlled trial
Live PubMed search
Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — meta-analysis
Live PubMed search
Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — pharmacokinetics
Live PubMed search
Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — safety adverse events
Live PubMed search
Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Choline-Stabilized Orthosilicic Acid (ch-OSA) — dose response
Live PubMed search
Live results for "Choline-Stabilized Orthosilicic Acid (ch-OSA) dose response" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Choline-Stabilized Orthosilicic Acid (ch-OSA) and "dose response". Filter by RCT, meta-analysis, or year on the results page.
Google Scholar: Choline-Stabilized Orthosilicic Acid (ch-OSA) — clinical evidence
Live Scholar search
Cross-database citation index for Choline-Stabilized Orthosilicic Acid (ch-OSA) as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.