Overview
Highest GLA content.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
GLA converts to DGLA, anti-inflammatory.
- · GLA converts to DGLA, anti-inflammatory
Effects on the body
Organ system effects
Borage Oil supports collagen synthesis, antioxidant defense, or barrier function in skin and integumentary tissues.
Evidence-based benefits
Improves RA symptoms
Moderate evidencePotential side effects
- · GI upset
- · PA contamination
Drug interactions
Supplement interactions
- Collagen peptidesProvides amino acid substrate for connective tissue synthesis.
- Vitamin CRequired cofactor for collagen hydroxylation.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified Borage Oil — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Borage Oil third party tested NSF
CapsulesPre-measured Borage Oil capsules — easiest for travel and consistent daily dosing without scoops or scales.Borage Oil capsules
PowderBulk unflavored Borage Oil powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Borage Oil powder unflavored
Best sellersMost-purchased Borage Oil products on Amazon — a quick way to see what's reviewed widely before you commit.Borage Oil best sellerScientific evidence8Show studiesHide studies
Borage for RA
Leventhal LJ, et al.
37 RA patients
Reduced joint tenderness.
PubMed: Borage Oil — Improves RA symptoms
Live PubMed search
Live results for "Borage Oil Improves RA symptoms" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Borage Oil and "Improves RA symptoms". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Borage Oil — randomized controlled trial
Live PubMed search
Live results for "Borage Oil randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Borage Oil and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Borage Oil — meta-analysis
Live PubMed search
Live results for "Borage Oil meta-analysis" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Borage Oil and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Borage Oil — pharmacokinetics
Live PubMed search
Live results for "Borage Oil pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Borage Oil and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Borage Oil — safety adverse events
Live PubMed search
Live results for "Borage Oil safety adverse events" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Borage Oil and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Borage Oil — dose response
Live PubMed search
Live results for "Borage Oil dose response" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Borage Oil and "dose response". Filter by RCT, meta-analysis, or year on the results page.
Google Scholar: Borage Oil — clinical evidence
Live Scholar search
Cross-database citation index for Borage Oil as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.