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Skin Health

Barrier function and dermal nutrition.

Ranked by evidence strength across reported benefits.

Vitamin#1· strong

Vitamin A (Retinol)

Fat-soluble vitamin essential for vision, immune function, and epithelial integrity.

Vitamin#2· strong

Vitamin B3 (Niacin)

NAD+ precursor; nicotinic acid form lowers LDL and raises HDL.

Vitamin#3· strong

Vitamin C

Water-soluble antioxidant, collagen cofactor, and immune supporter.

Amino Acid#4· strong

Glycine

Inhibitory amino acid that improves sleep quality, glycemic control, and collagen synthesis.

Vitamin#5· strong

Biotin (B7)

Coenzyme for carboxylases — popular for hair and nails despite weak data outside true deficiency.

Mineral#6· strong

Copper

Trace mineral cofactor for ceruloplasmin and connective tissue crosslinking.

Herb#7· strong

Gotu Kola (Extra)

Standardized triterpenes for venous insufficiency and skin healing.

Compound#8· strong

Marine Collagen (Extra)

Fish-derived type I collagen with high digestibility.

Mineral#9· strong

Copper Bisglycinate

Chelated copper used to balance high-dose zinc supplementation.

Mineral#10· moderate

Zinc

Cofactor for ~300 enzymes — critical for testosterone, immune function, and DNA synthesis.

Amino Acid#11· moderate

Glycine

Inhibitory neurotransmitter that improves sleep quality and supports collagen synthesis.

Vitamin#12· moderate

Vitamin E

Primary lipid-phase antioxidant protecting membrane PUFAs.

Compound#13· moderate

Collagen Peptides

Hydrolyzed protein supplying glycine, proline, and hydroxyproline for connective tissue.

Compound#14· moderate

Hyaluronic Acid

Glycosaminoglycan supporting skin hydration and joint lubrication.

Compound#15· moderate

Astaxanthin

Algal carotenoid that is the strongest membrane antioxidant; UV and eye protection.

Compound#16· moderate

Hyaluronic Acid (Oral)

GAG concentrated in synovial fluid — improves joint comfort and skin hydration.

Compound#17· moderate

Astaxanthin

Algae-derived xanthophyll — most potent natural antioxidant; UV/eye/skin support.

Compound#18· moderate

Verisol® Collagen Peptides

Specific bovine peptide blend marketed for skin and cellulite.

Compound#19· moderate

Astaxanthin (Eye dose)

Carotenoid that crosses BBB and accumulates in ciliary body.

Compound#20· moderate

Glutathione

Master intracellular antioxidant; oral bioavailability depends on form.

Herb#21· moderate

Gotu Kola

Adaptogen used for cognitive support, anxiety, and wound healing.

Compound#22· moderate

MSM (Methylsulfonylmethane)

Bioavailable sulfur donor for joints, skin, and hair-keratin synthesis.

Compound#23· moderate

Marine Collagen Peptides

Hydrolyzed fish collagen — supplies glycine, proline, and bioactive di/tripeptides for skin and hair.

Herb#24· moderate

Centella Asiatica (Gotu Kola)

Traditional brain and skin tonic — supports cognition and wound healing.

Vitamin#25· moderate

Niacinamide

Non-flushing B3 — used for deficiency, skin health, and at high doses in dermatology.

Vitamin#26· moderate

Biotin (Hair Dose)

B-vitamin used cosmetically for hair and nail growth.

Herb#27· moderate

Saw Palmetto

Lipidosterolic extract used for BPH urinary symptoms.

Herb#28· moderate

Spearmint Tea

Used for hirsutism in PCOS via mild anti-androgen effect.

Peptide#29· moderate

GHK-Cu (Copper Peptide)

Copper-binding tripeptide used topically for skin remodeling.

Vitamin#30· moderate

Tocotrienols (Skin/Aging)

Vitamin E isoforms with 40–60× higher antioxidant power than tocopherols.

Herb#31· moderate

Centella asiatica (Skin)

Standardized titrated extract for scars and venous skin changes.

Amino Acid#32· moderate

Glycine (Collagen Stack)

Free-form glycine paired with collagen for connective tissue synthesis.

Mineral#33· moderate

Zinc Bisglycinate (High-Bio)

Chelated zinc with superior absorption and tolerability.

Mineral#34· moderate

Choline-Stabilized Orthosilicic Acid (ch-OSA)

Highly bioavailable silica for hair, skin, and bone.

Herb#35· moderate

Centella Triterpene Fraction

Standardized madecassoside/asiaticoside for skin and venous health.

Peptide#36· moderate

TB-500 (Thymosin Beta-4)

Synthetic thymosin fragment for tissue repair.

Fatty Acid#37· moderate

Squalene

Olive oil/shark liver lipid antioxidant.

Amino Acid#38· moderate

L-Lysine

Essential amino acid for collagen and HSV prevention.

Mineral#39· moderate

Bamboo Silica

Plant-based silicon for skin and bones.

Mineral#40· moderate

Choline-Stabilized OSA

Bioavailable silicon form.

Compound#41· moderate

Astaxanthin (Haematococcus)

Algae carotenoid antioxidant.

Mushroom#42· moderate

Tremella Fuciformis

Snow fungus for skin hydration.

Nootropic#43· moderate

DMAE (Dimethylaminoethanol)

Choline analog for cognition.

Compound#44· moderate

Type III Collagen

Skin and vascular collagen.

Compound#45· moderate

Marine Collagen Peptides

Fish-derived collagen.

Compound#46· moderate

Bovine Collagen Peptides

Cow-derived collagen hydrolysate.

Compound#47· moderate

Hyaluronic Acid (Oral)

Oral HA for skin and joints.

Compound#48· moderate

OptiMSM

Distilled MSM for joints.

Vitamin#49· moderate

Biotin (High-Dose)

High-dose for MS and hair.

Compound#50· moderate

MSM (Methylsulfonylmethane)

Organic sulfur for joints and skin.

Compound#51· moderate

Grape Seed Extract

Vitis vinifera procyanidins.

Compound#52· moderate

Manuka Honey

Leptospermum honey with MGO.

Vitamin#53· moderate

Liposomal Vitamin C

Phospholipid-encapsulated vitamin C.

Vitamin#54· moderate

Ascorbyl Palmitate

Fat-soluble vitamin C ester.

Fatty Acid#55· moderate

Evening Primrose Oil

GLA omega-6 for skin and PMS.

Fatty Acid#56· moderate

Borage Oil

Highest GLA content.

Fatty Acid#57· moderate

Blackcurrant Seed Oil

GLA + ALA omega-3/6.

Fatty Acid#58· moderate

Hemp Seed Oil

3:1 omega-6 to omega-3 ratio.

Vitamin#59· limited

Vitamin B7 (Biotin)

Carboxylase cofactor marketed for hair, skin, and nail support.

Fatty Acid#60· limited

Evening Primrose Oil

Omega-6 source rich in GLA, used for atopic dermatitis and cyclical breast pain.

Vitamin#61· limited

Vitamin B5 (Pantothenic acid)

Component of coenzyme A, central to fatty acid and acetylcholine synthesis.

Mineral#62· limited

Silica (Silicon)

Trace element involved in collagen and connective tissue crosslinking.

Herb#63· limited

Horsetail Extract

Silica-rich herb traditionally used for hair, nail, and connective tissue support.

Mineral#64· limited

Zinc Picolinate

Zinc chelated to picolinic acid — one of the most bioavailable oral forms.

Mineral#65· limited

Zinc Bisglycinate

Glycine-chelated zinc — high absorption and very gentle on the stomach.

Peptide#66· limited

Biotinyl Tripeptide-1 (Procapil)

Topical peptide complex marketed for hair anchoring.