Overview
Traditional brain and skin tonic — supports cognition and wound healing.
- Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
- Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
- Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Forms & variants of Centella Asiatica (Gotu Kola)
Different chemical forms of Centella Asiatica (Gotu Kola) behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Asiaticosides upregulate collagen synthesis and BDNF.
- · Asiaticosides upregulate collagen synthesis
Effects on the body
Organ system effects
Evidence-based benefits
Improves wound healing and scarring
Moderate evidenceMild anxiolytic
Limited evidencePotential side effects
- · Centella Asiatica (Gotu Kola) is generally well-tolerated at evidence-based doses
- · Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
- · Headache or transient fatigue reported by a small fraction of users
- · Allergic or hypersensitivity reaction (rash, itching, swelling)
- · Sleep disturbance if taken late in the day
- · Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Centella Asiatica (Gotu Kola) — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Centella Asiatica (Gotu Kola) third party tested NSF
CapsulesPre-measured Centella Asiatica (Gotu Kola) capsules — easiest for travel and consistent daily dosing without scoops or scales.Centella Asiatica (Gotu Kola) capsules
PowderBulk unflavored Centella Asiatica (Gotu Kola) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Centella Asiatica (Gotu Kola) powder unflavored
Best sellersMost-purchased Centella Asiatica (Gotu Kola) products on Amazon — a quick way to see what's reviewed widely before you commit.Centella Asiatica (Gotu Kola) best sellerScientific evidence9Show studiesHide studies
Centella asiatica for anxiety
Bradwejn J, et al.
RCT of Centella on acoustic startle response.
Reduced acute anxiety response.
PubMed: Centella Asiatica (Gotu Kola) — Improves wound healing and scarring
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PubMed: Centella Asiatica (Gotu Kola) — Mild anxiolytic
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PubMed: Centella Asiatica (Gotu Kola) — randomized controlled trial
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PubMed: Centella Asiatica (Gotu Kola) — pharmacokinetics
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PubMed: Centella Asiatica (Gotu Kola) — dose response
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Google Scholar: Centella Asiatica (Gotu Kola) — clinical evidence
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