Brain & Mental Performance
Focus, memory, mood, and neuroprotection.
Creatine Monohydrate
The most-studied and effective ergogenic aid — replenishes ATP via the phosphocreatine system.
Vitamin D3
Steroid hormone precursor regulating ~5% of the human genome — bone, immune, and hormonal health.
Ashwagandha
Adaptogenic herb that down-regulates HPA-axis output — lowers cortisol, supports T in stressed men.
Omega-3 (EPA/DHA)
Marine long-chain omega-3s — the most-studied anti-inflammatory and cardiovascular nutrient.
Curcumin
Yellow polyphenol from turmeric — anti-inflammatory and joint-supportive when properly bioavailable.
L-Carnitine
Shuttles long-chain fatty acids into mitochondria for β-oxidation.
L-Theanine
Calm focus — alpha-wave amino acid from green tea that takes the edge off caffeine.
Lion's Mane
Edible medicinal mushroom that upregulates NGF and BDNF — studied for nerve growth and cognition.
N-Acetyl Cysteine (NAC)
Glutathione precursor with mucolytic, hepatoprotective, and psychiatric uses.
Rhodiola Rosea
Arctic adaptogen — reduces fatigue and improves mental performance under stress.
Vitamin B12
Essential cobalamin for methylation, red blood cell formation, and myelin maintenance.
5-HTP
Direct serotonin precursor with mood and sleep applications.
Alpha-GPC
Bioavailable choline source studied for cognition and acute power output.
American Ginseng
Cooler adaptogen with stronger evidence for blood sugar and cold-flu prevention.
CBD (Cannabidiol)
Non-intoxicating cannabinoid studied for anxiety, sleep, and seizures.
Caffeine
Adenosine antagonist with strong evidence for cognitive and physical performance.
Centella Asiatica (Gotu Kola)
Traditional brain and skin tonic — supports cognition and wound healing.
Choline
Essential nutrient for cell membranes, methylation, and acetylcholine synthesis.
Cistanche Tubulosa
Desert plant tonic for libido and cognition.
Citicoline (CDP-Choline)
Phospholipid precursor with cytidine bonus — supports membranes and dopamine.
Folate (Vitamin B9)
One-carbon donor essential for DNA synthesis and neural tube development.
Ginkgo Biloba
Vasoactive herb studied for cognition in the elderly and tinnitus.
Gotu Kola
Adaptogen used for cognitive support, anxiety, and wound healing.
Holy Basil (Tulsi)
Ayurvedic adaptogen with anti-stress, anti-inflammatory, and glycemic effects.
Kanna (Sceletium)
South African succulent acting as SSRI + PDE4 inhibitor for mood and stress.
L-Theanine (Sleep)
Tea-derived amino acid that raises alpha brainwaves — relaxation without sedation.
L-Tyrosine (Dopamine Replenishment)
Catecholamine precursor — replenishes dopamine/norepinephrine pools after stimulant use.
Mucuna Pruriens
Natural L-DOPA source studied for mood, libido, and Parkinson's.
Mucuna Pruriens (Fertility)
L-DOPA-containing legume — improves sperm parameters and dopaminergic tone.
Mucuna Pruriens (Velvet Bean)
Natural L-DOPA source studied for Parkinson's, libido, and fertility.
Myo-Inositol
Insulin sensitizer used for PCOS and anxiety/OCD support.
Panax Ginseng
Adaptogenic ginseng studied for fatigue, cognition, and erectile function.
Passionflower
Mild anxiolytic and sleep aid with GABA-A modulation.
Phosphatidylserine (PS)
Phospholipid that supports cognition and may blunt cortisol response to stress.
Rhodiola Rosea
Arctic adaptogen for mental fatigue, burnout, and stress resilience.
SAMe (S-Adenosyl Methionine)
Universal methyl donor with antidepressant and liver-supportive evidence.
Saffron
Culinary spice with antidepressant effects comparable to SSRIs in mild-moderate depression.
Salvia officinalis (Sage)
Culinary sage with cholinergic and anti-hyperhidrosis effects.
Vitamin B1 (Thiamine)
Cofactor for carbohydrate metabolism and nerve conduction.
Vitamin B6 (Pyridoxine)
Cofactor for >100 enzymes including neurotransmitter synthesis.
5-HTP (Post-MDMA Replenishment)
Serotonin precursor — used post-MDMA to support depleted 5-HT stores. Never combine same-day.
5-HTP (Sleep Use)
Serotonin → melatonin precursor — supports sleep onset and depth.
6-Shogaol (Ginger)
Bioactive ginger compound.
9-Me-BC
β-carboline alkaloid that upregulates dopamine neurons in animal models.
Agmatine Sulfate
Arginine metabolite with NMDA modulation and analgesic properties.
Algae Omega-3
Vegan EPA/DHA source.
Algal Omega-3 (Vegan EPA/DHA)
Plant-based EPA and DHA from microalgae for vegan diets.
Allithiamine
Garlic-derived fat-soluble thiamine.
Alpha-GPC (Cholinergic Recovery)
Choline source — supports acetylcholine after stimulant-driven depletion.
Aniracetam
Fat-soluble racetam.
Apigenin
Chamomile/parsley flavonoid — GABA-A modulator and CD38 inhibitor for sleep and NAD+.
Ashwagandha (Cortisol Lowering)
Validated cortisol-lowering adaptogen — ~28% reduction in chronically stressed adults.
Ashwagandha KSM-66
Standardized Withania somnifera root extract for stress.
BCM-95 Curcumin
Curcumin with turmeric oils for absorption.
Bacopa CDRI-08
Standardized Bacopa monnieri extract for memory.
Bacopa Monnieri
Ayurvedic nootropic with strong evidence for memory consolidation over 8–12 weeks.
Baicalin
Scutellaria baicalensis flavonoid.
Bifidobacterium Longum 1714
Psychobiotic for stress and mood.
Biotin (High-Dose)
High-dose for MS and hair.
Blue Vervain
Verbena hastata for nervous tension and headache.
Butterbur
Petasites hybridus extract for migraine prophylaxis and allergic rhinitis.
CDP-Choline (Citicoline)
Phospholipid precursor for cognition.
CDP-Choline (Citicoline)-Stroke
Acute stroke neuroprotection.
California Poppy
Mild sedative with anxiolytic and analgesic activity.
California Poppy
Eschscholzia californica for anxiety and insomnia.
Centrophenoxine
Cholinergic precursor that reduces lipofuscin accumulation in neurons.
Chamomile
Gentle anxiolytic and sleep-supportive herb.
Chinese Skullcap
Flavonoid-rich root used for anxiety and inflammation.
Choline Bitartrate
Affordable choline source — supports phospholipid synthesis and methylation.
Coluracetam
Racetam acting on high-affinity choline uptake; studied for depression/anxiety.
DHA-Dominant Fish Oil
High-DHA for brain health.
DL-Phenylalanine
Catecholamine precursor with mild analgesic properties.
DL-Phenylalanine (DLPA)
Racemic phenylalanine for pain and mood.
DMAE (Dimethylaminoethanol)
Choline analog for cognition.
EPA-Dominant Fish Oil
Concentrated EPA for inflammation.
Enzogenol
New Zealand pine bark extract.
Ergothioneine (Mushroom-Derived)
Natural ergothioneine from oyster mushrooms.
Folinic Acid (Leucovorin)
Reduced folate form.
GABA
Primary inhibitory neurotransmitter; oral supplementation has limited CNS penetration.
GOS (Galactooligosaccharides)
Galactose-based prebiotic.
Galantamine (Plant-Derived)
Snowdrop alkaloid AChE inhibitor.
Ginkgo Biloba EGb 761
Standardized Ginkgo for cognition.
Guanfacine (Ref)
α2A-agonist reference drug for prefrontal focus and ADHD.
Holy Basil (Tulsi)
Ocimum sanctum adaptogen.
Honokiol
Active magnolia compound.
Huperzine A
Acetylcholinesterase inhibitor from club moss — potent cholinergic enhancer.
Idebenone
Synthetic CoQ10 analog with better water solubility; used in LHON.
Kava
Polynesian anxiolytic with strong evidence; rare hepatotoxicity risk.
Kratom (caution)
Atypical opioid herb with stimulant low-dose and sedating high-dose effects; addiction risk.
L-Phenylalanine
Precursor to tyrosine and catecholamines.
L-Tryptophan
Essential amino acid precursor to serotonin and melatonin.
L-Tyrosine
Catecholamine precursor preserving cognition under stress and sleep deprivation.
L-Tyrosine (Thyroid Substrate)
Amino acid substrate paired with iodine to form thyroid hormones.
L. helveticus R0052
Psychobiotic blend component for mood.
Lavender Oil (Silexan)
Oral lavender essential oil with proven anxiolytic effect.
Lemon Balm
Mild anxiolytic with cognitive calming effects via GABA-T inhibition.
Lemon Balm Melissa Officinalis (Bluenesse)
Standardized Melissa for cognition.
Lion's Mane (Neuroregeneration)
NGF-upregulating mushroom — included in post-use stacks for neurotrophic support.
Lion's Mane Erinacines
Hericium erinaceus mycelium for NGF.
Lion's Mane Fruiting Body
Hericinones-rich beta-glucan source.
Lithium Orotate (low-dose)
Low-dose lithium salt studied for mood stability and neuroprotection.
Longvida Curcumin
SLCP curcumin for brain bioavailability.
Luteolin
Flavone with anti-inflammatory effects.
MCT C8 (Caprylic Acid)
Pure C8 medium-chain triglyceride for ketone production.
Magnesium L-Threonate
Mg form designed for brain penetration; studied for cognition and sleep.
Magnolia Bark
GABAergic anxiolytic bark extract used for sleep and stress.
Magnolol
Active magnolia biphenol.
Methylcobalamin High-Dose
Active B12 form for neuropathy.
Modafinil (Rx note)
Wakefulness-promoting Rx — listed for reference; not a supplement.
Modafinil (Rx, reference)
Wakefulness-promoting agent — listed for reference only (prescription drug).
Mucuna Pruriens
Velvet bean providing natural L-DOPA.
Mulungu
Erythrina mulungu bark for anxiety relief.
Myo-Inositol (High-Dose)
High-dose for psychiatric uses.
NAC (Post-Use Recovery)
GSH precursor — supports glutamatergic rebalancing and oxidative stress recovery after stimulant or psychedelic use.
Noopept
Synthetic dipeptide (peptide-like) studied for cognition and neuroprotection; not FDA approved.
Noopept (GVS-111)
Russian dipeptide nootropic.
Ocimum Tenuiflorum (OciBest)
Standardized Holy Basil for stress.
Oxiracetam
Racetam for cognition.
PQQ
Cofactor stimulating mitochondrial biogenesis (PGC-1α).
PharmaGABA
Naturally fermented GABA.
Phenibut (caution)
GABA-B agonist with high abuse and dependence potential; restricted in many countries.
Phenylpiracetam
Racetam + phenethylamine moiety — stimulant-like nootropic with rapid tolerance.
Phenylpiracetam Hydrazide
Hydrazide analog of phenylpiracetam reported to support memory and locomotion.
Phosphatidylcholine
Membrane phospholipid for liver.
Phosphatidylcholine (PC)
Major brain and hepatic phospholipid often given for liver support.
Picamilon
Niacin-GABA conjugate.
Piracetam
Original racetam; modulates AMPA receptors and membrane fluidity. Rx in many countries.
Pramiracetam
Racetam family — increases high-affinity choline uptake.
Pregnenolone
Master steroid precursor; small doses studied for cognition and PTSD.
Pycnogenol (Pine Bark)
French maritime pine bark for circulation.
Pyritinol
Pyridoxine derivative for cognition.
Rhodiola SHR-5
Standardized Rhodiola for fatigue.
Rosemary (Cognitive)
Rosmarinus officinalis for memory and mood via inhalation or oral.
Saffron Affron
Standardized saffron for mood.
Saffron Satiereal
Saffron for appetite and snacking.
Salmon Roe Phospholipids
Phospholipid omega-3s from salmon eggs.
Selank
Russian anxiolytic peptide based on tuftsin.
Semax
Russian nootropic ACTH analog for cognitive enhancement.
Shoden Ashwagandha
35% withanolide glycoside Ashwagandha for sleep.
Soy Lecithin
Phosphatidylcholine source.
St. John's Wort
Mild-moderate antidepressant with significant CYP450 drug interactions.
Sulbutiamine
Lipid-soluble thiamine derivative crossing the BBB for fatigue and focus.
Suntheanine
Pharmaceutical-grade L-theanine.
Theracurmin
Nano-particle curcumin for bioavailability.
Turmeric Essential Oil
Ar-turmerone for brain regeneration.
Uridine Monophosphate
Pyrimidine nucleoside — supports phosphatidylcholine synthesis and dopamine receptor density.
Uridine Monophosphate
Pyrimidine that supports synaptic membrane synthesis.
Valerian Root
Sedative herb traditionally used for sleep onset and mild anxiety.
Valerian Root
GABAergic sedative herb — modest sleep onset benefit.
Vinpocetine
Periwinkle alkaloid that increases cerebral blood flow.
Vitamin B2 (Riboflavin)
FAD/FMN precursor central to redox reactions and migraine prophylaxis.
Ziziphus (Jujube Seed)
Traditional Chinese seed extract for insomnia and anxiety.