Mood & Anxiety
Neurotransmitter and HPA modulation.
Vitamin D3
Steroid hormone precursor regulating ~5% of the human genome — bone, immune, and hormonal health.
Ashwagandha
Adaptogenic herb that down-regulates HPA-axis output — lowers cortisol, supports T in stressed men.
Omega-3 (EPA/DHA)
Marine long-chain omega-3s — the most-studied anti-inflammatory and cardiovascular nutrient.
L-Theanine
Calm focus — alpha-wave amino acid from green tea that takes the edge off caffeine.
Lion's Mane
Edible medicinal mushroom that upregulates NGF and BDNF — studied for nerve growth and cognition.
N-Acetyl Cysteine (NAC)
Glutathione precursor with mucolytic, hepatoprotective, and psychiatric uses.
Rhodiola Rosea
Arctic adaptogen — reduces fatigue and improves mental performance under stress.
5-HTP
Direct serotonin precursor with mood and sleep applications.
CBD (Cannabidiol)
Non-intoxicating cannabinoid studied for anxiety, sleep, and seizures.
Folate (Vitamin B9)
One-carbon donor essential for DNA synthesis and neural tube development.
Gotu Kola
Adaptogen used for cognitive support, anxiety, and wound healing.
Holy Basil (Tulsi)
Ayurvedic adaptogen with anti-stress, anti-inflammatory, and glycemic effects.
Kanna (Sceletium)
South African succulent acting as SSRI + PDE4 inhibitor for mood and stress.
Mucuna Pruriens
Natural L-DOPA source studied for mood, libido, and Parkinson's.
Myo-Inositol
Insulin sensitizer used for PCOS and anxiety/OCD support.
Passionflower
Mild anxiolytic and sleep aid with GABA-A modulation.
Saffron
Culinary spice with antidepressant effects comparable to SSRIs in mild-moderate depression.
Vitamin B6 (Pyridoxine)
Cofactor for >100 enzymes including neurotransmitter synthesis.
5-HTP (Post-MDMA Replenishment)
Serotonin precursor — used post-MDMA to support depleted 5-HT stores. Never combine same-day.
Agmatine Sulfate
Arginine metabolite with NMDA modulation and analgesic properties.
Aniracetam
Fat-soluble racetam.
Ashwagandha KSM-66
Standardized Withania somnifera root extract for stress.
BCM-95 Curcumin
Curcumin with turmeric oils for absorption.
Bacopa Monnieri
Ayurvedic nootropic with strong evidence for memory consolidation over 8–12 weeks.
Baicalin
Scutellaria baicalensis flavonoid.
Bifidobacterium Longum 1714
Psychobiotic for stress and mood.
Blue Vervain
Verbena hastata for nervous tension and headache.
California Poppy
Mild sedative with anxiolytic and analgesic activity.
California Poppy
Eschscholzia californica for anxiety and insomnia.
Chamomile
Gentle anxiolytic and sleep-supportive herb.
Chinese Skullcap
Flavonoid-rich root used for anxiety and inflammation.
Coluracetam
Racetam acting on high-affinity choline uptake; studied for depression/anxiety.
DL-Phenylalanine
Catecholamine precursor with mild analgesic properties.
DL-Phenylalanine (DLPA)
Racemic phenylalanine for pain and mood.
EPA-Dominant Fish Oil
Concentrated EPA for inflammation.
GABA
Primary inhibitory neurotransmitter; oral supplementation has limited CNS penetration.
Holy Basil (Tulsi)
Ocimum sanctum adaptogen.
Honokiol
Active magnolia compound.
Kava
Polynesian anxiolytic with strong evidence; rare hepatotoxicity risk.
Kratom (caution)
Atypical opioid herb with stimulant low-dose and sedating high-dose effects; addiction risk.
L-Phenylalanine
Precursor to tyrosine and catecholamines.
L-Tryptophan
Essential amino acid precursor to serotonin and melatonin.
L-Tyrosine
Catecholamine precursor preserving cognition under stress and sleep deprivation.
L. helveticus R0052
Psychobiotic blend component for mood.
Lavender Oil (Silexan)
Oral lavender essential oil with proven anxiolytic effect.
Lemon Balm
Mild anxiolytic with cognitive calming effects via GABA-T inhibition.
Lemon Balm Melissa Officinalis (Bluenesse)
Standardized Melissa for cognition.
Lithium Orotate (low-dose)
Low-dose lithium salt studied for mood stability and neuroprotection.
Magnolia Bark
GABAergic anxiolytic bark extract used for sleep and stress.
Magnolol
Active magnolia biphenol.
Mucuna Pruriens
Velvet bean providing natural L-DOPA.
Mulungu
Erythrina mulungu bark for anxiety relief.
Myo-Inositol (High-Dose)
High-dose for psychiatric uses.
NAC (Post-Use Recovery)
GSH precursor — supports glutamatergic rebalancing and oxidative stress recovery after stimulant or psychedelic use.
Ocimum Tenuiflorum (OciBest)
Standardized Holy Basil for stress.
PharmaGABA
Naturally fermented GABA.
Phenibut (caution)
GABA-B agonist with high abuse and dependence potential; restricted in many countries.
Picamilon
Niacin-GABA conjugate.
Pregnenolone
Master steroid precursor; small doses studied for cognition and PTSD.
Rhodiola SHR-5
Standardized Rhodiola for fatigue.
Rosemary (Cognitive)
Rosmarinus officinalis for memory and mood via inhalation or oral.
Saffron Affron
Standardized saffron for mood.
Saffron Satiereal
Saffron for appetite and snacking.
Selank
Russian anxiolytic peptide based on tuftsin.
Shoden Ashwagandha
35% withanolide glycoside Ashwagandha for sleep.
St. John's Wort
Mild-moderate antidepressant with significant CYP450 drug interactions.
Suntheanine
Pharmaceutical-grade L-theanine.
Uridine Monophosphate
Pyrimidine that supports synaptic membrane synthesis.
Valerian Root
Sedative herb traditionally used for sleep onset and mild anxiety.
Ziziphus (Jujube Seed)
Traditional Chinese seed extract for insomnia and anxiety.