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Bifidobacterium Longum 1714

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Bifidobacterium Longum 1714. Psychobiotic for stress and mood.

How it works. Modulates HPA axis via vagus nerve.

What the research supports. 1 graded claims. Strongest: Reduces stress response (moderate).

How much to take. Typical dose: 1 billion CFU.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Multi-strain probiotic, L-glutamine.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Bifidobacterium Longum 1714. Anecdotes are not medical advice.

Bifidobacterium Longum 1714. Psychobiotic for stress and mood.

No single structure

What it is

Psychobiotic for stress and mood.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

Mood & Anxiety

How it works

Modulates HPA axis via vagus nerve.

Pathways

  • Modulates HPA axis via vagus nerve

Effects

  • ↓stress response decreases

What the research supports

Reduces stress responsemoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
1 billion CFU
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodWith a meal containing fat for fat-soluble compounds; otherwise either.
Best formMost evidence is based on the capsule or softgel form.
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Side effects & interactions

Common side effects

  • Mild GI

Medication interactions

Prescription medications (general)minor

Always disclose Bifidobacterium Longum 1714 use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Bifidobacterium Longum 1714 — Reduces stress response ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Bifidobacterium Longum 1714 and "Reduces stress response". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Bifidobacterium Longum 1714 — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Bifidobacterium Longum 1714 and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Bifidobacterium Longum 1714 — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Bifidobacterium Longum 1714 and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

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