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Nootropic

Phenylpiracetam Hydrazide

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Phenylpiracetam Hydrazide. Hydrazide analog of phenylpiracetam reported to support memory and locomotion.

How it works. Putative AMPA modulator; precise mechanism uncharacterized in humans.

What the research supports. 1 graded claims. Strongest: Animal models show locomotor enhancement (limited).

How much to take. Typical dose: 100–200 mg (experimental).

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Omega-3 (EPA/DHA), Alpha-GPC or CDP-choline.

Common forms. Available as Capsule, Powder for stacking, Sublingual tablet, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Phenylpiracetam Hydrazide. Anecdotes are not medical advice.

Phenylpiracetam Hydrazide. Hydrazide analog of phenylpiracetam reported to support memory and locomotion.

Molecular structureC12H15N3O2 · 233.27 g/mol

What it is

Hydrazide analog of phenylpiracetam reported to support memory and locomotion.

Also called

Fonturacetam hydrazide

Food sources

Manufactured pharmaceutical-grade compoundStandardized botanical extract (for plant-derived nootropics)Stack formulations combined with cholinergic or adaptogenic ingredients

Goals

Brain & CognitiveAthletic Performance

How it works

Putative AMPA modulator; precise mechanism uncharacterized in humans.

Pathways

  • Putative AMPA modulator
  • precise mechanism uncharacterized in humans

Effects

  • +Animal models show locomotor enhancement supports

What the research supports

Animal models show locomotor enhancementlimited

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
100–200 mg (experimental)
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither with or without food.
Best formMost evidence is based on the capsule form.
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Side effects & interactions

Common side effects

  • Irritability

Medication interactions

Prescription medications (general)minor

Always disclose Phenylpiracetam Hydrazide use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
  • Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.

Common forms

  • Capsule
  • Powder for stacking
  • Sublingual tablet
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Phenylpiracetam Hydrazide — Animal models show locomotor enhancement ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "Animal models show locomotor enhancement". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Phenylpiracetam Hydrazide — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Phenylpiracetam Hydrazide — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Phenylpiracetam Hydrazide and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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